Endemic goiter is clustered occurrences of goiter affecting more than 10% of the population in particular regions. The majority cases are attributed to environmental factors such as iodine deficiency, or food and water containing goiter-causing agents called goitrogens. We report a new type of endemic goiter where the basic abnormality was not due to environment factors, but to thyroglobulin ge...

The presence of substernal goiter is, per se, an indication for surgical management. Surgical approach of substernal goiter can most commonly be performed using the cervical access, but at times, a sternotomy or thoracotomy is necessary. The aim of this study was to identify the preoperative predictors of a sternotomy in the management of substernal goiter in order to provide better preoperativ...

OBJECTIVES We comprehensively estimated the prevalence of goiter and thyroid nodules (TNs) before and after the implementation of the Universal Salt Iodization (USI) program in mainland China and provided information for creating effective health policies. METHODS PubMed, Google Scholar, CNKI, Chinese Wanfang and Chongqing VIP databases were searched for relevant studies from Jan 1985 to Feb ...

OBJECTIVE To describe quantitative cytophotometric expression of the marker caspase-3 in colloid goiter and in papillary carcinoma of the thyroid, comparing the immunoexpression between them. METHODS An immunohistochemistry study has been made on the protein caspase-3 in 17 of paraffin blocks of papillary carcinoma of the thyroid and 20 cases of colloid goiter, using SAMBA 4000 ® (System of M...

background: some studies have shown the possible role of protein‑energy malnutrition (pem) in persistence of endemic goiter in iodine replenished areas. the present study was conducted to assess the association between pem and goiter in schoolchildren of isfahan, iran. methods: in a cross‑sectional study using multistage cluster random‑sampling, 2331 schoolchildren with age ranged from 6‑13 yea...

introduction : in order to evaluate the role of thyroid autoimmunity in patients with goiter, this study was done 10 years after implementation of iodine supplementation program ( iodised salt). the serum levels of thyroid peroxidase antibodies (anti tpo) and thyroglobulin antibodies (anti tg) were studied in a group of patients with simple goiter and compared with normal controls. materials an...

According to previous studies, Turkey has generally been accepted as a moderate endemic iodine deficient country. However, it has recently been reported that there are regions in Turkey where iodine deficiency is more severe than previously known. The current study was aimed at ascertaining the goiter prevalence by thyroid volumes, iodine status and thyroid functions in school-age children livi...

UNLABELLED The term of retrosternal or substernal goiter means that more than 50% of thyroid gland descends in the thorax. MATERIAL AND METHODS There is a retrospective study on retrosternal and substernal goiter and its patological features among 2482 patients who underwent thyroidectomy between 2000 and 2010 in the First Surgery Clinic of Iaşi. Retrosternal goiter was identified 54 patients...

Background: The normal thyroid gland is a fairly homogenous structure, but nodules often formed within its substance these nodule may be the growth and fusion of localized colloid – filled follicles, or discrete adenomas, or cyst. The terms adenomatous goiter, simple multi nodular goiter, non toxic nodular goiter, and colloid nodular goiter are used interchangeably as descriptive terms when a m...

A study was conducted in a Community Development Block area, a valley between the offshoots of the Chilarai Hills, situated at a distance of 45 Km from Guwahati city. Eight villages were selected in the block for the study and family members of every 4 family of each village was interviewed and clinically examined for goiter. Total numbers of individuals examined were 1424. Overall goiter preva...