OBJECTIVE Evaluation of the relationship between umbilical coiling index (UCI) and adverse perinatal outcome. METHOD A prospective study was performed on 699 pregnant women who were 37-40 weeks. UCI was determined by dividing the total number of the complete vascular coiling by the total umbilical cord length in centimeters. Then the relationship between UCI and neonatal weight, amniotic flui...

OBJECTIVE Assess the association between meconium-stained amniotic fluid and chorioamnionitis or endometritis in term pregnant women. MATERIAL AND METHOD A five-year retrospective study was undertaken between January 1, 1999 and December 31, 2003. One thousand seventy-nine pregnant women who delivered at the Department of Obstetrics & Gynecology, Phramongkutklao Hospital were included in the ...

We have isolated carcinoembryonic antigen (CEA)-related antigens from meconium and compared them with those in adult feces. Two CEA-related antigens were detected in meconium [nonspecific cross-reacting antigen 2 (NCA-2) and meconium nonspecific cross-reacting antigen] while four CEA-related antigens were found in adult feces [normal fecal antigen 1, normal fecal antigen 2 (NFA-2), normal fecal...

BACKGROUND Meconium aspiration syndrome (MAS) is defined by respiratory distress requiring supplemental oxygen in a meconium-stained neonate. MAS is clinically subclassified as mild, moderate, and severe according to the oxygen requirement. The aims of this study were to compare the histological findings in the placentas of MAS neonates with those of meconium-stained but non-MAS neonates and to...

OBJECTIVE To see the effect of amnioinfusion on perinatal outcome in cases of meconium staining of liquor. METHODS This study was conducted in department of Obstetrics and Gynaecology, unit 1, Jinnah Postgraduate Medical Centre, Karachi, from 1st January 1998 to 31st December 2000. Four hundred patients were included in this study, assigning 200 for amnioinfusion and 200 as control. All patie...

OBJECTIVES This study aimed to find out the risk factors leading meconium aspiration syndrome in patients having meconium-stained amniotic fluid. METHODOLOGY comparative was conducted department of Obstetrics and Gynaecology at Hayatabad Medical Complex from January 2022- June 2022. All admitted labour ward with diagnosis liquor (MSL) were included through a convenient sampling technique. Patie...

Specimens of meconium and random stools were collected sequentially from 25 healthy newborn babies over the first 8-14 days of life. The stool chymotrypsin concentrations increased from birth to a maximum at 4 days of age and then fell again over the next four days. The lowest individual stool concentrations either side of the four day peak were both, coincidentally, 120 micrograms/g stool. In ...

Meconium aspiration syndrome (MAS) is a common problem that most pediatricians will encounter in the delivery room and normal newborn nursery. Approximately 13% of all live births are complicated by meconium stained amniotic fluid (MSAF). MAS is defined as respiratory distress in an infant born through MSAF whose symptoms cannot be otherwise explained. Optimal care for an infant born through MS...

We describe an unexplained case of umbilical cord segmental hemorrhage linked with meconium-stained amniotic fluid. A severely asphyxiated infant was delivered at term by Caesarean section. There were poor prognostic signs on fetal cardiotocography with rupture of membranes with meconium-stained amniotic fluid. The pathophysiologic mechanism in this case is still unknown, even if we argued a po...

Background: Meconium is not only a potential sign of fetal hypoxia but is also a potential toxin if the fetus aspirates particulate matters with a gasping breath in utero or when it takes its first breaths following birth. In addition to this the condition of the mother who gives birth in such circumstances is a concern. Methods: A hospital based cross-sectional descriptive study was carried ou...