The objective of this study was to evaluate a method for predicting daily protein accretion rates of various genotypes of pigs reared in different environmental conditions using easily obtained mean daily fat-free growth rates. Data were obtained for seven genotype-environment groups of gilts and nine groups of barrows. Daily empty body protein accretion rates were estimated at 1.0-kg intervals...

OBJECTIVE Several studies show that patients undergoing total knee arthroplasty (TKA) tend to maintain or gain weight after the procedure, which would result in increased wear of the prosthesis and new surgical interventions in a smaller period of time in comparison with patients with adequate body mass index (BMI). The aim of this study was to investigate the effect of TKA surgery on these pat...

AIM To compare the effects of inhaled and systemic steroids on growth in very low birthweight (VLBW) infants with chronic lung disease (CLD). METHODS Sixteen babies with CLD randomly received inhaled budesonide (100 microg four times daily for 10 days via Aerochamber) or systemic steroids (dexamethasone 0.5 mg/kg/day, reducing over nine days). Linear growth (lower leg length, LLL) was measure...

The first U.S. nationwide food sampling with measurement of dioxins, dibenzofurans, and coplanar, mono-ortho and di-ortho polychlorinated biphenyls (PCBs) is reported in this study. Twelve separate analyses were conducted on 110 food samples divided into pooled lots by category. The samples were purchased in 1995 in supermarkets in Atlanta, GA, Binghamton, NY, Chicago, IL, Louisville, KY, and S...

CONTEXT Zonisamide is a marketed antiepileptic drug that has serotonergic and dopaminergic activity in addition to blockade of sodium and calcium channels. Weight loss was an adverse effect associated with zonisamide treatment in epilepsy clinical trials. OBJECTIVE To evaluate the efficacy of zonisamide for weight loss in obese adults. DESIGN AND SETTING Sixteen-week randomized, double-blin...

BACKGROUND The prevalence of morbid obesity is increasing rapidly. Weight reduction is very difficult using diet restriction and physical activity alone. Sibutramine has been shown to be effective and safe as an adjuvant therapy to diet restrictions. OBJECTIVES To describe our experience using sibutramine in weight reduction treatment of adolescents suffering from morbid obesity. METHODS Th...

BACKGROUND Behavioral interventions for obesity produce clinically meaningful weight loss, but weight regain following treatment is common. Extended care programs attenuate weight regain and improve weight loss maintenance. However, less is known about the most effective ways to deliver extended care, including contact schedules. METHODS We compared the 12-month weight regain of an extended c...

BACKGROUND Observational studies report that as students transfer from secondary school to university, there is a tendency to gain weight. This phenomenon is known as the "Freshman 15" in North America, referring to the claim that on average weight gain is 15 lb (6.8 kg) in the first year of university. Studies since 1985 have mostly found weight gains ranging from 1 kg to 6 kg. Our meta-analys...

AIM As weight gain and hypoglycaemia associated with glimepiride therapy can negatively impact weight perceptions, psychological well-being and overall quality of life in type 2 diabetes, we investigated whether liraglutide treatment could improve these factors. METHODS Seven hundred and thirty-two patients with type 2 diabetes completed a 77-item questionnaire during a randomized, 52-week, d...

STUDY OBJECTIVE To assess changes in the body mass index (BMI, weight (kg)/height2 (m2)) and in the prevalence of obesity in Swedish women during the 1980s. DESIGN Data from two successive cross sectional surveys were used. SETTING The whole of Sweden. SUBJECTS A total of 7419 women from a 1980-81 survey (response rate 84.6%) and 6306 women from a 1988-89 survey (response rate 80.3%), age...