نتایج جستجو برای: mdl
تعداد نتایج: 1822 فیلتر نتایج به سال:
RESUMO Este estudo buscou analisar, para o caso brasileiro, Mecanismo de Desenvolvimento Limpo (MDL). Usou-se conceito externalidade negativa e falha mercado entender a necessidade políticas ambientais capazes favorecer desenvolvimento sustentável dos países. Os resultados mostraram importância da escala registro projetos. O setor energia, por exemplo, tem mais projetos pequena que foram criado...
MDL 62,879 (GE2270A) 1 is a new inhibitor of elongation factor-Tu (EF-Tu) and belongs to the class of thiazolyl peptide antibiotics. Controlled acid hydrolysis of 1 followed by treatment with base resulted in the lost of the two terminal amino acids and in the formation of water-soluble MDL 62,935 2. Although less active in vitro than its parent compound, 2 was able to inhibit by 50% an Escheri...
The Minimum Description Length (MDL) principle is the modern formalisation of Occam’s razor. It has been extensively and successfully used in machine learning (ML), especially for noisy and long sources of data. However, the MDL principle presents some paradoxes and inconveniences. After discussing these all, we address two of the most relevant: lack of explanation and lack of creativity. We pr...
UNLABELLED Calpain is an intracellular Ca²⁺-activated protease that is involved in numerous Ca²⁺ dependent regulation of protein function in many cell types. This paper tests a hypothesis that calpains are involved in Ca²⁺-dependent increase of the late sodium current (INaL) in failing heart. Chronic heart failure (HF) was induced in 2 dogs by multiple coronary artery embolization. Using a conv...
A human monocytic cell line, THP-1, stimulated with 40 nM phorbol myristate acetate (PMA), differentiated to macrophage-like cells, and exhibited increased expression and release of interleukin-1 beta and expression of acetylated low density lipoprotein (ac-LDL) receptors. A selective inhibitor, MDL 29,152 (4-propyl-5-(4-quinolinyl)-2(3H)-oxazolone) was used to show that this induction required...
Sirlusoidal sigrial detcctkm is discussed in various fields rangir~g frorri telec:orr~rr~ur~ic~~t,io~~s to array processirlg and spectrurri estirriation. Various tecl~rliques have bee11 proposed in the literat,ure for si~iusoidal sigrlal detection arid enurrieratior~; see [I]. Here, we propose two er~urr~eratior~ teclmiques b e d or1 the rr~inirriurr~ tlcscriptivr~ ler~glit (MDL) [2] and the pr...
We address an original statistical method for unsupervised identification and concentration estimation of spectrally interfering gas components of unknown nature and number. We show that such spectral unmixing can be efficiently achieved using information criteria derived from the Minimum Description Length (MDL) principle, outperforming standard information criteria such as AICc or BIC. In the...
For spline smoothing one can rewrite the smooth estimation as a linear mixed model (LMM) where the smoothing parameter appears as the variance of spline basis coefficients. Smoothing methods that use basis functions with penalization can utilize maximum likelihood (ML) theory in LMM framework ([8]). We introduce the minimum description length (MDL) model selection criterion in LMM and propose a...
The minimum description length (MDL) criterion for model selection has been successfully applied to the problem of estimating the number of sources in noise. We show that by employing an order statistics approach in the existing solution, a new processor with uniformly improved performance is constructed at the cost of greater complexity. We prove that the resulting MDL-based processor is consi...
We show how partial models of natural language syntax (manually written DCGs, with parameters estimated from a parsed corpus) can be automatically extended when trained upon raw text (using MDL). We also show how we can use a parsed corpus as an alternative constraint upon estimation. Empirical evaluation suggests that a parsed corpus is more informative than a MDL-based prior. However , best r...
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