The in vivo fate of various “In-labeled polypeptides has been the subject of many investigations. Intracellular metabolism has been StUdied through the use of “In-labeled glycoproteins that are concentrated in the lysosome by receptor-mediated endocytosis. These studies have Indicated that the main lysosomal metabolite is “In-chelate-e-lysine, both in vitro and in vivo (Y. Arano et aL, J....

 Korea’s youth unemployment problem has continued to worsen since 2004. According to an E24, J64, an analysis of raw data from Statistics Korea’s Economically Active Population Survey and Supplementary Results of the Economically Active Population Survey on Youths to confirm whether youth unemployment affects all youths, more youths were delaying graduation or taking leaves of absence due t...

Piritrexim, a new nonclassical antifolate, was evaluated in a multiinstitutional phase I trial in children. The starting dose was 290 mg/m2/ day, administered p.o. every 12 h for 5 consecutive days, with courses repeated every 21 days. Dose reduction, initially to 200 mg/m2/day and subsequently to 140 mg/m2/day, was required because dose limiting myelosuppression and mucositis were encountered ...

The purpose of this article is analyse the Entrepreneurial Ecosystem Guadalajara Jalisco, México (EEZMG) through its technology-based, fast growing startups and ‘entrepreneurial-employees’, their growth dynamics interactions as well to explore factors that impact growth, discover policies or programs have greatest effect on development. Therefore, using analytical framework ‘Entrepreneur...

C —¿ > T transitions at CpG sites are the most prevalent mutations found in the p53 tumor suppressor gene in human colon tumors and in the germline (Li-Fraumeni syndrome). All of the mutational hot spots are methylated to 5-methylcytosine, and it has been hypothesized that the majority of these mutations are caused by spontaneous hydrolytic deamination of this base to thymine. We have previou...

Insulin-like growth factor (IGF) I has important growth regulatory functions in normal growth and development. IGF-I is also a mitogen for a number of cancer cell lines; however, its autocrine effect has not been well established. In this study, the expression of IGF-I, its receptor, and its major serum-binding protein were examined in 5 normal human mesothelial (NHM) cell samples and 11 pleura...

Cocoa butter was crystallized statically from the melt to various temperatures in the range of -20 to 26 °C and annealed for up to 45 days. During this period, the polymorphism of the solid state was monitored using differential scanning calorimetry and powder X-ray diffraction. Moreover, the microstructure of the materials was imaged using polarized light microscopy. Below -15 °C, a mixture of...

ofthe various factors that go into the computation better; it also segregates the least reliable and error-prone model-dependent components into terms that can be identified and minimized. Regional cerebral glucose utilization is calcu lated as: IT C@†• (T) †" K'I' I C@(t) e@ +k@)(Tt) dt JO (IfTC(t) fTC@(t) e@ +k@)(Tt) dt)-@-dt-i; 0 @ 0 Eq.! where C@' represents total concentration of ‘4C...

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