نتایج جستجو برای: maturation division

تعداد نتایج: 150823  

Journal: :The EMBO journal 2004
Maria Paola Paronetto Ezio Giorda Rita Carsetti Pellegrino Rossi Raffaele Geremia Claudio Sette

Vertebrate eggs arrest at metaphase of the second meiotic division before fertilization under the effect of a cytostatic factor (CSF). This arrest is established during oocyte maturation by the MAPK kinase module, comprised of Mos, MEK, MAPKs and p90Rsk. Maintenance of CSF arrest at metaphase requires inhibitors of the anaphase-promoting complex (APC) like Emi1, which sequesters the APC activat...

2013
Felix Bärenz Daigo Inoue Hideki Yokoyama Justus Tegha-Dunghu Stephanie Freiss Stefanie Draeger Dmytro Mayilo Ivana Cado Sabine Merker Maren Klinger Burkhard Hoeckendorf Sahra Pilz Kerstin Hupfeld Herbert Steinbeisser Holger Lorenz Thomas Ruppert Joachim Wittbrodt Oliver J. Gruss

Meiotic maturation in vertebrate oocytes is an excellent model system for microtubule reorganization during M-phase spindle assembly. Here, we surveyed changes in the pattern of microtubule-interacting proteins upon Xenopus laevis oocyte maturation by quantitative proteomics. We identified the synovial sarcoma X breakpoint protein (SSX2IP) as a novel spindle protein. Using X. laevis egg extract...

2004
Maria Paola Paronetto Ezio Giorda Rita Carsetti Pellegrino Rossi Raffaele Geremia Claudio Sette

Vertebrate eggs arrest at metaphase of the second meiotic division before fertilization under the effect of a cytostatic factor (CSF). This arrest is established during oocyte maturation by the MAPK kinase module, comprised of Mos, MEK, MAPKs and p90. Maintenance of CSF arrest at metaphase requires inhibitors of the anaphase-promoting complex (APC) like Emi1, which sequesters the APC activator ...

Journal: :The Journal of reproduction and development 2009
Masahiro Yoshizawa Hiroyuki Watanabe Yutaka Fukui

The aim of this study was to investigate the effects of the presence and the numbers of corpora lutea (CL) in porcine ovaries on in vitro oocyte maturation and embryonic development following intracytoplasmic sperm injection (ICSI). At oocyte collection, the ovaries of non-delivered and delivered pigs were classified into four groups by CL presence. The effect of the number of CL was also inves...

Journal: :Journal of Chemical Education 1993

Journal: :international journal of reproductive biomedicine 0
reza mahmoudi aligholi subhani mozhdeh salehnia farideh etesam parichehr pasbakhsh farid abolhasani

background: in vitro maturation (ivm) of oocytes is a promising technique to reduce the costs and avert the side-effects of gonadotropin stimulation for in vitro fertilization (ivf). the pregnancy rates from oocytes matured in vitro are much lower than those of in vivo stimulation cycles, indicating that optimization of ivm remains a challenge. objective: in this study, we investigated the effe...

ژورنال: طب کار 2019

Introduction: Occupational Dermal exposure to Antineoplastic Drugs is the one of the most important routes in Healthcare staffs. Several antineoplastic drugs have been classified as carcinogens by the International Agency for Research on Cancer (IARC). Regards to this issue investigation on Dermal exposure to Antineplastic Drugs in healthcare staffs is nessessary. Method: In this Descriptive a...

پایان نامه :وزارت علوم، تحقیقات و فناوری - دانشگاه صنعتی خواجه نصیرالدین طوسی - دانشکده مهندسی مکانیک 1392

مخازن تحت فشار کاربرد فراوان در صنایع شیمیایی، اتمی و موشکی دارند. طراحی این محفظه ها می بایست از دقت و ضریب اطمینان بالایی برخوردار باشد چرا که خطرات ناشی از طراحی نادرست که نتیجه آن انهدام محفظه می باشد از لحاظ جانی و مالی بسیار گران تمام خواهد شد، به همین منظور لازم است که از روش استانداردی جهت طراحی محفظه ها استفاده نمود. جهت طراحی محفظه های تحت فشار می بایست از استانداردهایی استفاده شود ک...

2017
George Komis Ivan Luptovčiak Miroslav Ovečka Despina Samakovli Olga Šamajová Jozef Šamaj

Katanin is the only microtubule severing protein identified in plants so far. Previous studies have documented its role in regulating cortical microtubule organization during cell growth and morphogenesis. Although, some cell division defects are reported in KATANIN mutants, it is not clear whether or how katanin activity may affect microtubule dynamics in interphase cells, as well as the progr...

خان بابایی, رمضان , فرهادی محلی , سمانه,

Background and Purpose: In vitro maturation of oocyte is a promising technology in treatment of infertility, however, its clinical application is still limited due to poor success rate. This study was devised to evaluate the effect of mouse embryo tail bud co-culture on maturation of immature mouse oocyte. Materials and Methods: Immature oocytes were recovered from NMRI female mice 48hr after ...

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