Introduction: Preeclampsia is a condition of hypertension that occurs after 20 weeks gestation, followed by the detection protein in urine sample, and one major causes maternal mortality. It categorized, based on time into 2-stage are early late-onset. One more accessible tools diagnosing also preventing preeclampsia its risk factors. The aim this study was to observe appearance some factors pa...

OBJECTIVE To evaluate the association between maternal pre-pregnancy body mass index (BMI) and the risk of stillbirth and neonatal death and to study the causes of death among the children. DESIGN Cohort study of pregnant women receiving routine antenatal care in Aarhus, Denmark. SETTING Aarhus University Hospital, Denmark, 1989-1996. POPULATION A total of 24,505 singleton pregnancies (11...

Maternal obesity programmes offspring development. We addressed maternal obesity effects induced by high-fat diets on maternal mammary gland (MG) structure and function and offspring brain, liver and fat outcomes. Mothers were fed control (C, n 5) or obesogenic (MO, n 5) diet from the time they were weaned through pregnancy beginning at 120 d, through lactation. At offspring postnatal day (PND)...

BACKGROUND Perinatal stress may programme overweight and obesity. We examined whether maternal pre- and post-natal bereavement was associated with overweight and obesity in young men. METHODS A cohort study was conducted including 119,908 men born from 1976 to 1993 and examined for military service between 2006 and 2011. Among them, 4,813 conscripts were born to mothers bereaved by death of a...

BACKGROUND Breastfeeding behaviour is multifactorial, and a wide range of socio-cultural and physiological variables impact on a woman's decision and ability to breastfeed successfully. An association has been reported between maternal obesity and low breastfeeding rates. This is of public health concern because obesity is rising in women of reproductive age and the apparent association with in...

In developed countries in women of reproductive age an increase in obesity levels has been widely reported with an associated increase in maternal obesity (Yu et al, 2006, Heslehurst et al, 2008, Huda et al, 2010). Obesity in pregnancy is associated with an increased incidence of medical complications including gestational diabetes mellitus, pre-eclampsia and venous thromboembolism (Huda et al,...

Obesity during pregnancy contributes to the development of metabolic disorders in offspring. Maternal exercise may limit gestational weight gain and ameliorate these programming effects. We previously showed benefits of post-weaning voluntary exercise in offspring from obese dams. Here we examined whether voluntary exercise during pregnancy influences lipid and glucose homeostasis in muscle and...

Much has been written about the rise in Caesarean section rates seen worldwide and in Ireland. The recent ESRI paper 1 suggested that physician behaviour might be an important factor in Ireland. The study concluded that changes in maternal characteristics accounted for only about half of the increase in Caesarean section rates but it did not include maternal obesity in the analysis (the data ar...

Development of CKD may be programmed prenatally. We sought to determine the association of childhood CKD with prenatal risk factors, including birth weight, maternal diabetes mellitus (DM), and maternal overweight/obesity. We conducted a population-based, case-control study with 1994 patients with childhood CKD (<21 years of age at diagnosis) and 20,032 controls in Washington state. We linked m...

BACKGROUND The intrauterine environment may influence the development of obesity, but as yet, the long-term effect of growth in utero is unclear. We studied maternal smoking during pregnancy to gain insight on how an insult affecting fetal growth might subsequently influence obesity risk through childhood to age 33. METHODS Data from the 1958 British birth cohort (all births in England, Wales...