INTRODUCTION Abdominal pregnancy is a rare form of ectopic pregnancy with a high rate of maternal and fetal complications. Most of the reported cases are diagnosed in early trimesters, usually after presenting with complications. Advanced abdominal pregnancy poses a huge diagnostic and management challenge, particularly in low-income countries. A term abdominal pregnancy diagnosed pre-operative...

background: when fetal red cells enter the maternal circulation from placenta, an event would be happened that is described as feto-maternal hemorrhage (fmh). this life-threatening condition could be detected by using rbc antigens (surface antigens and intracellular antigens). therefore, the measurement of fetal rbc in an artificial model would be useful to calculate fmh and consequently the do...

OBJECTIVES The purpose of this study was to determine whether cardiac complications of neonatal lupus erythematosus (NLE) are related to maternal anti-Ro and anti-La autoantibody-levels. BACKGROUND Autoantibody-positive mothers are frequently referred for serial echocardiography because of the elevated fetal risk of developing immune-mediated heart block. Little is known why only some and not...

In recent decades, our understanding of the disrupted mechanisms that contribute to major obstetrical diseases, including preeclampsia, fetal growth restriction, preterm birth, and gestational diabetes, has increased exponentially. Common many these obstetric diseases is placental maldevelopment dysfunction; placenta a significant component maternal–fetal interface involved in coordinating, fac...

Background & Aims: Due to the importance of a suitable treatment for nausea and vomiting during pregnancy and reducing maternal and fetal complications, and the beneficial effect of Ondansetron in the treatment of nausea and vomiting compared with promethazine, this study was performed. Methods: In this case-control study, 60 pregnant women under 20 weeks of gestation with hyperemesis gravidaru...

BACKGROUND Treatment of maternal tachyarrhythmias in pregnancy is a major clinical issue. Pharmacological treatment raises important concerns regarding partial efficacy and side effects. Radiofrequency ablation of arrhythmogenic substrate has rarely been performed during pregnancy because of the fetal risks related to x-ray exposure and potential fetomaternal procedural complications. CASES T...

OBJECTIVES To assess the delivery outcome in a pregnancy with a previous unexplained intra-uterine death by elective induction of labour at term. METHODS An audit of the pregnancy outcome of all women within the catchment area with a current singleton pregnancy; and a previous unexplained or unexplored singleton fetal demise ≥24 weeks (or 500 grams birth weight if gestation unknown) after pla...

The human fetal immune system is naturally exposed to maternal allogeneic cells, maternal antibodies, and pathogens. As such, it is faced with a considerable challenge with respect to the balance between immune reactivity and tolerance. Here, we show that fetal natural killer (NK) cells differentiate early in utero and are highly responsive to cytokines and antibody-mediated stimulation but res...

The patterns of association between maternal or paternal and neonatal phenotype may offer insight into how neonatal characteristics are shaped by evolutionary processes, such as conflicting parental interests in fetal investment and obstetric constraints. Paternal interests are theoretically served by maximizing fetal growth, and maternal interests by managing investment in current and future o...