OBJECTIVE Spinal deformity surgery has the potential risk of massive blood loss. To reduce surgical bleeding, the use of tranexamic acid (TXA) became popular in spinal surgery, recently. The purpose of this study was to determine the effectiveness of intra-operative TXA use to reduce surgical bleeding and transfusion requirements in spinal deformity surgery. METHODS A total of 132 consecutive...

PURPOSE OF REVIEW Severe trauma is associated with hemorrhage, coagulopathy and transfusion of blood and blood products, all associated with considerable mortality and morbidity. The aim of this review is to focus on resuscitation, transfusion strategies and the management of bleeding in trauma as well as to emphasize on why coagulation has to be monitored closely and to discuss the rationale o...

T rauma is the leading cause of death in individuals between the ages of 5 and 45 years worldwide and is expected to become the second leading cause of death by 2020 across all age groups. Nationally, approximately 1 out of every 1000 Americans is hospitalized annually for injuries sustained secondary to trauma, with these patients receiving approximately 10% to 15% of the 14.6 million red bloo...

abstract a32 year-old multigravid patient with 10 weeks of pregnancy was referred to the emergency ward with massive vaginal bleeding and preshock state. suction curettage, laparotomy, uterine artery ligation, macdonald cerclage, and hysterectomy was done, in that order. after hysterectomy and massive transfusion she recovered. when a diagnosis of cesarean scar pregnancy is made in the emergenc...

e third edition of Transfusion Th erapy: Clinical Principles and Practice picks up where previous editions have left off . It also continues in the book’s tradition as an easily readable and facile reference for the critical care provider who needs to use blood component therapy in the care of their patients. Th is work, edited by Paul D Mintz, a pathologist-expert in blood banking from Th e Un...

As the title implies, massive transfusion is not without risks-though the need for such treatment is regularly evidenced. The authors detail the changes which occur in the blood during the process of its being drawn, anticoagulated, and stored. The clinical significance of these changes and other complications are presented, along with their manifestations and treatment. Finally, a rational app...

a survey of tissue oxygenation differences in intensive care patients with blood transfusion     haghighimoghadamy [1] *, valizadeh ma [2] , feizi a [3]     received: 26 dec, 2011 accepted: 7 mar, 2012     abstract   background & aims : greater than 75% patient that hospitalized in intensive care units has anemia. blood transfusion in icu is not recently and about 40-70% patients in intensive c...