We have determined that the gene for human microtubule-associated protein 2 (MAP-2) spans 19 exons, including 6 exons identified in this study, 1-4, 8, and 13; all six of these exons are transcribed. The alternative splicing of coding exons generates a greater diversity of MAP-2 transcripts and isoforms. The first three exons encode alternate 5' untranslated regions that can be spliced to addit...

This study investigated the role of various types of content representation devices on the comprehension of an expository hypertext. We hypothesized that hierarchical representations, but not network representations, may help low prior knowledge students organize their representation of the text contents. Forty-seven students with low or high prior knowledge in Social Psychology were asked to r...

While the senior population has been increasingly engaged with reading on mobile technologies, research that specifically documents the impact of technologies on reading for this age group has still been lacking. The present study investigated how different reading media (screen versus paper) might result in different reading outcomes among older adults due to both cognitive and psychological f...

We present a new, accurate and efficient tool for mapping short reads obtained from the Illumina Genome Analyzer following sodium bisulfite conversion. Our tool, BRAT, supports single and paired-end reads and handles input files containing reads and mates of different lengths. BRAT is faster, maps more unique paired-end reads and has higher accuracy than existing programs. The software package ...

The cartogram, or value-by-area map, is a popular technique for cartographically representing social data. Such maps visually equalize a basemap prior to mapping a social variable by adjusting the size of each enumeration unit by a second, related variable. However, to scale the basemap units according to an equalizing variable, cartograms must distort the shape and/or topology of the original ...

Spatial descriptions symbolically represent environmental information through language and are written in two primary perspectives: survey, analogous to viewing a map, and route, analogous to navigation. Readers of survey or route descriptions form abstracted perspective flexible representations of the described environment, or spatial mental models. The present two experiments investigated the...

We have determined the complete nucleotide sequence of a 5783-base pair segment of adenovirus type 2 DNA, located between map coordinates 15.8 and 31.7. This region of the adenovirus-2 genome encodes the three segments of the tripartite leader, the i-leader and the two species of virus-associated RNA. The established sequence reveals two translational reading frames encoded by the viral 1-stran...

We present a graphical criterion for reading dependencies from the minimal directed independence map G of a graphoid p when G is a polytree and p satisfies composition and weak transitivity. We prove that the criterion is sound and complete. We argue that assuming composition and weak transitivity is not too restrictive.

eQTL: expression Quantitative Trait Loci; GAD: Genetic Association Database; GtEx: Genotype-tissue Expression; HapMap: Haploid Map; HGNC: Human Genome Nomenclature Committee; HPRD: Human Protein Reference Database; HPA: Human Protein Atlas; MOPED: Model Organism Protein Expression Database; PheGenI: Phenotype-Genotype Integrator; ORF: Open Reading Frame; RefSeq: Reference Sequence; SNP: Single ...

A genomic analysis of 18 P. aeruginosa phages, including nine newly sequenced DNA genomes, indicates a tremendous reservoir of proteome diversity, with 55% of open reading frames (ORFs) being novel. Comparative sequence analysis and ORF map organization revealed that most of the phages analyzed displayed little relationship to each other.