Streptococcus pneumoniae requires manganese for colonization of the human host, but the underlying molecular basis for this requirement has not been elucidated. Recently, it was shown that zinc could compromise manganese uptake and that zinc levels increased during infection by S. pneumoniae in all the niches that it colonized. Here we show, by quantitative means, that extracellular zinc acts i...

Analysis of data obtained from the national hydrochemical survey show that about 42% of tubewells have manganese concentrations exceeding the WHO health-based guideline value of 0.4 mg/l. High manganese concentrations in groundwater have been found in the central, northern, and western regions of Bangladesh; groundwater in the north-eastern region of Bangladesh contain relatively less manganese...

High-dose human exposure to manganese results in manganese accumulation in the basal ganglia and dopaminergic neuropathology. Occupational manganese neurotoxicity is most frequently linked with manganese oxide inhalation; however, exposure to other forms of manganese may lead to higher body burdens. The objective of this study was to determine tissue manganese concentrations in rhesus monkeys f...

In this research, the stoichiometric perovskite lead titanate (PbTiO3) nanostructurewas synthesized successfully by the hydrothermal method. The effect of heattreatment of the autoclave and the furnace on the structure of this materialwas investigated. Titanium dioxide (TiO2), titanium tetrachloride (TiCl4) and leadoxide (PbO), lead nitrate (Pb(NO3)2) were used as the ti...

Concerns have been raised regarding environmental manganese exposure since high exposures have been associated with neurological disorders. The USA Environmental Protection Agency most recent human health risk assessment of inhaled manganese conducted in 1993 identified specific areas of uncertainty regarding manganese pharmacokinetics. This led to the development of a test rule under the USA C...

This review provides an overview of the role, routes and effects of manganese in aquatic crustaceans. Manganese is a naturally abundant metal in marine and freshwater sediments where it is involved in a large number of chemical processes. Although sediments contain high natural concentrations of manganese, the potential danger to benthic organisms has been neglected in studies to date. Manganes...

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Permanganate-Based Synthesis of Semiconducting Metal Oxide Nanoparticles in the Protein Ferritin Cameron Olsen Department of Physics and Astronomy, BYU Bachelor of Science This thesis investigates the reactions of Mn2+ and Co2+ with permanganate as a route for manganese and cobalt oxide nanoparticle synthesis in the protein ferritin. Permanganate serves as the electron acceptor and reacts with ...

The toxicokinetics of manganese (Mn) was investigated in male and female rats either following a single intravenous (iv) or oral dose of MnCl2 (6.0 mg Mn/kg), or following a single oral dose of methylcyclopentadienyl manganese tricarbonyl (MMT) (20 mg MMT/kg or 5.6 mg Mn/kg). The plasma concentrations of manganese were quantified by atomic absorption spectrophotometry (AAS). Upon iv administrat...