OBJECTIVE To determine the linezolid clearance and serum concentrations in a critically ill man receiving continuous venovenous hemodiafiltration (CVVHDF). METHODS Intravenous linezolid 600 mg every 12 hours was administered to a critically ill, 85-year-old man with anuria who was receiving CVVHDF at a dialysate flow rate of 2000 ml/hour and a mean ultrafiltrate production rate of 775 ml/hour...

Cumulative evidence indicates that the hippocampus plays a time-limited role in contextual learning paradigms. Pharmacological studies have indicated that acquisition of background contextual cues during Pavlovian fear conditioning is dependent upon hippocampal function, whereas early inactivation of the hippocampus after training produces retrograde amnesia. When administered prior to contextu...

Cloud computing focuses on delivery of reliable, Fault-tolerant and scalable infrastructure for hosting Internet based application services. Cloud computing has become a new age technology that has got huge potentials in enterprises and markets. Clouds can make it possible to access applications and associated data from anywhere. Resource allocation is one of the important challenges in cloud c...

Background: Covid-19 epidemia is a worldwide infectious viral disease initiating from December 2019from Wuhan, China. Recognition of the prognostic role imaging findings important to improve theoutcomes in patients. Accordingly, regarding lack studies this era among Iranian patients, studywas done determine association between CT scan and mortality cases.Methods: In prospective cohort study, 19...

Recent studies of adults have found evidence for consolidation effects in the acquisition of novel words (Dumay & Gaskell, 2007), but little is known about whether such effects are found developmentally. In two experiments we familiarized children with novel nonwords (e.g., biscal) and tested their recognition and recall of these items. In Experiment 1 7-year old children were then retested eit...

The long-bone fractures occur most frequently in the tibial shaft. Adequate treatment of such fractures avoids consolidation failure, skewed consolidation and reoperation. To classify these fractures, the AO/OTA classification method is still used, but it is worthwhile getting to know the Ellis classification method, which also includes assessment of soft-tissue injuries. There is often an asso...

Histone acetylation has recently been implicated in learning and memory processes, yet necessity of histone acetylation for such processes has not been demonstrated using pharmacological inhibitors of histone acetyltransferases (HATs). As such, the present study tested whether garcinol, a potent HAT inhibitor in vitro, could impair hippocampal memory consolidation and block the memory-enhancing...

Unit labor cost (ULC) is defined as labor compensation per value added. It captures the cost competitiveness of industries and countries. As labor compensation is wage multiplied by hours worked or number of people employed, it is easy to show that ULC is wage divided by labor productivity. Thus, changes in ULC are often discussed in the context of wage increases and labor productivity. However...

growing evidence suggests that serotonin plays an important role in learning and memory and all its receptors might be implicated in this process. the present study aimed at investigating and comparing the possible involvement of 5-ht 3 and 5-ht 4 receptor (r) agonists/antagonists upon consolidation of inhibitory avoidance memory in the pre-limbic (pl) area. bilateral intra-pl microinjections o...

We present a case of delayed presentation of a subdural haematoma causing cauda equina syndrome which occurred 96 hours after a spinal anaesthetic had been administered for an elective total hip replacement in an 86-year-old man. The patient had received low-molecular-weight heparin anticoagulation which had been delayed until 12 hours postoperatively. No other cause of the haemorrhage could be...