Introduction: Leishmaniasis is a disease with high mortality rates and approximately 1.5 million new cases each year. Despite the approaches advances to fight disease, there are no effective therapies. Methods: Hence, this study aims screen for natural products' structural analogs as drug candidates against leishmaniasis. We applie...

Background: Musa acuminata (Musaceae) is a perennial tree-like plant that grown in many tropical and subtropical areas throughout the globe. Bananas, which may be consumed as fruit or vegetable, one of most significant crops nations owing to their nutrient-dense diet diverse therapeutic properties. Introduction: Apigenin glycosides, myricetin glycoside, myricetin-3-O-rutinoside, delphinidin, pe...

The World Health Organization predicts over a 70% increase in cancer incidents in developing nations over the next decade. Although these nations have limited access to novel therapeutics, they do have access to foods that contain chemopreventive bioactive compounds such as anthocyanins, and as such, consumption of these foods can be encouraged to combat cancer. We and others have previously ch...

Despite the actual therapeutic approaches for inflammatory bowel disease (IBD), efficient and secure alternative options remain a research focus. In this context, anthocyanins seem promising natural anti-inflammatory agents, but their action mechanisms and efficacy as compared with established drugs still require more clarification. The main aim of this study was to compare the anti-inflammator...

Hybrid cellulose-poly(4-vinylpyridine) particles (MCC-P(4VP)) were synthesized via ATRP grafting and used as adsorbents to target polyphenols in residues derived from winemaking, olive oil production almond processing. These hybrid preserve good conditions be continuous sorption/desorption processes assessed for the retention of solvent mixtures ranging 0 100% water content. Other seven these a...

Hibiscus syriacus is a highly ornamental flowering shrub widely grown in East Asia. Its abundant flower colors mainly reflect the accumulation of anthocyanins. Classifying H. petals and identifying relationship between color anthocyanins can provide references for breeding. With eight cultivars as experimental materials, floral was described using Royal Horticultural Society Color Chart CIEL*a*...

Hypothesis Anthocyanins possess well-known biological effects and suppress DNA damage induced by therapeutic topoisomerase poisons. Our study focusses on the modulatory effects of anthocyanidins-malvidin (MAL) and pelargonidin (PEL)-on topoisomerase II poison mitoxantrone (MXT)-induced cytotoxicity and genotoxicity in in vitro and in vivo conditions. Study design HepG2 cells were treated with M...

The goal of eating five servings of fruits and vegetables a day has not yet been achieved. The intake of polyphenols such as anthocyanins (ACN) could be improved by consuming smoothies and juices that are increasingly popular, especially in children; however, bioavailability data concerning food matrix effects are scarce. Thus, we conducted a randomised, cross-over, bioavailability study (n 10)...

Anthocyanins, flavan-3-ols, and flavonols are the three major classes of flavonoid compounds found in grape berry tissues. Several viticultural practices increase flavonoid content in the fruit, but the underlying genetic mechanisms responsible for these changes have not been completely deciphered. The impact of post-veraison sunlight exposure on anthocyanin and flavonol accumulation in grape b...