نتایج جستجو برای: malignant meningioma m0337826

تعداد نتایج: 216991  

Journal: :International journal of oncology 2007
Padmaja Tummalapalli Christopher S Gondi Dzung H Dinh Meena Gujrati Jasti S Rao

Meningiomas are the most commonly occurring tumors of the central nervous system including the brain and spinal cord. Malignant meningiomas are highly aggressive and frequently recur after surgical resection of the tumor. Our previous studies have reported that urokinase plasminogen activator receptor (uPAR) and matrix metalloproteinase-9 (MMP-9) play important roles in tumor progression. In th...

Journal: :JPMA. The Journal of the Pakistan Medical Association 1999
R Ahmed I N Soomro S A Aziz S H Hasan

OBJECTIVE Alterations: p53 genes are turning out to be the most common genetic alterations in human cancers. Due to long half-life of mutated p53, its detection is possible by immunohistochemistry. Proliferating cell nuclear antigen (PCNA) is expressed by dividing cells, hence has been shown to correlate with prognosis. We have used monoclonal antibodies protein DO-7 (p53) and PC10 (PCNA) to se...

2011
Juliette Randerson-Moor Kairen Kukalizch

Characterised by families with cutaneous malignant melanoma (CMM) and nervous system tumours. Initially described in a family with malignant melanoma and/or cerebral astrocytoma in eight members over three generations. Astroctytomas and cutaneous malignant melanoma have been identified in a number of well defined syndromes such as neurofibromatosis, Turcot’s, Lynch type II cancer, LiFraumeni an...

2011
Juliette Randerson-Moor Kairen Kukalizch D Timothy Bishop

Characterised by families with cutaneous malignant melanoma (CMM) and nervous system tumours. Initially described in a family with malignant melanoma and/or cerebral astrocytoma in eight members over three generations. Astroctytomas and cutaneous malignant melanoma have been identified in a number of well defined syndromes such as neurofibromatosis, Turcot’s, Lynch type II cancer, LiFraumeni an...

2017
Marwan W. Najjar Nour H. Abdul Halim Fares R. Sukhon Bassem Youssef Hazem I. Assi

BACKGROUND Meningiomas are slow-growing tumors attached to the dura mater and are composed of neoplastic meningothelial cells. The tumors are most commonly located in convexities, and it is relatively rare to find such a growth in the parietal region such as the one presented in this case report. CASE REPORT Because of its uncommon presentation, we hereby report the case of a 67-year-old, previ...

2014
Fumihiro MATANO Koji ADACHI Yasuo MURAI Takayuki KITAMURA Ryuji OHASHI Akira TERAMOTO Akio MORITA

Microcystic meningiomas are rare but benign brain tumors. Previous reports have shown that Thallium-201 single-photon emission computed tomography ((201)Tl SPECT) demonstrated a higher late-phase accumulation of (201)Tl in malignant or recurrent meningiomas than in nonaggressive meningiomas. No study has reported (201)Tl SPECT findings in microcystic meningiomas. We here describe a case of a mi...

Journal: :Brain pathology 2010
Yohan Lee Jason Liu Shilpa Patel Timothy Cloughesy Albert Lai Haumith Farooqi David Seligson Jun Dong Linda Liau Donald Becker Paul Mischel Soheil Shams Stanley Nelson

Meningiomas are one of the most common adult brain tumors. For most patients, surgical excision is curative. However, up to 20% recur. Currently, the molecular determinants predicting recurrence and malignant transformation are lacking. We performed retrospective global genetic and genomic analysis of 85 meningioma samples of various grades. Copy number alterations were assessed by 100K single-...

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