Usually, malignant melanoma is readily diagnosed by the presence of melanin granules. Although amelanotic melanoma contains a few melanin granules, it is often difficult to differentiate from non-epithelial malignant tumours. This report describes a case of amelanotic melanoma of the vagina, which was originally suspected to be a non-epithelial malignant tumour, but was subsequently correctly d...

https://doi.org/10.4068/cmj.2017.53.1.78 C Chonnam Medical Journal, 2017 Chonnam Med J 2017;53:78-80 Corresponding Author: Luca Roncati Department of Diagnostic and Clinical Medicine and of Public Health, Section of Pathology, University of Modena and Reggio Emilia, Policlinico Hospital, I-41124 Modena (MO), Italy Tel: +390594224812, Fax: +390594224998, E-mail: [email protected] Article Hi...

Melanoma has been reported a contemporary malignant cancer. Here, anti-cancer effects of sea cucumber extract (SCE) have been examined on melanoma cells and compared with dacarbazine. MTT assay and morphological analysis were performed to evaluate cytotoxic effects of methanolic SCE Also, several methods were exerted to detect cell dying by SCE and dacarbazine. The MTT assay showed that B16F10 ...

Although rare, malignant melanoma occurs in children. The risk of degeneration of a congenital melanocytic nevus into a melanoma is approximately 0.7%. We report a case of malignant melanoma that developed on a congenital melanocytic nevus in a 19-month-old boy. The child was treated by surgical resection, superficial parotidectomy, and modified radical neck dissection with adjuvant therapy. Th...

AMA Grzegorczyk A, Marczyńska Z, Matkowski R, et al. Severe complications of nivolumab monotherapy in an adolescent with malignant melanoma. Central European Journal Immunology. 2023. doi:10.5114/ceji.2023.130864. APA Grzegorczyk, A., Marczyńska, Z., Matkowski, R., Ziętek, M., Pietras, W., & Latos-Grażyńska, E. (2023). https://doi.org/10.5114/ceji.2023.130864 Chicago Aleksandra, Zuzanna Rafał M...

A case of primary malignant melanoma of the conus medullaris depicted at MR imaging is presented. Tumoral histoimmunologic analysis revealed features of malignant melanoma. Because findings for primary melanoma outside the spinal cord were negative, the diagnosis of primary intramedullary malignant melanoma was established. This rare tumor should be suspected when T1-weighted images show signal...

A 49-year-old Caucasian woman presented to the dermatology clinic for follow-up of malignant melanoma with a complaint of painless gross hematuria. Two years prior she was diagnosed with malignant melanoma from a skin lesion on her left flank treated with wide excision, negative axillary sentinel lymph node biopsy, and adjuvant radiotherapy. Subsequently, she had no evidence of disease until ur...

Primary subglottic malignant melanoma is a very rare and underdiagnosed neoplasm. We are reporting a case of primary malignant melanoma of subglottic mucosa in a 78-year-old woman who presented to our hospital with shortness of breath and hoarseness of voice. Laryngoscopy and excisional biopsy along with immunoreactivity to S-100 and human melanoma black-45 (HMB-45) confirmed the diagnosis. The...

Malignant melanoma of the mandibular gingiva is extremely rare. It is a malignant tumour of melanocytes or their precursor cells, and often misinterpreted as a benign pigmented process. A few reports have described computed tomography (CT) and magnetic resonance imaging (MRI) findings of malignant melanoma in the oral cavity. We report a rare case of malignant melanoma of the mandible and the r...

Mucosal malignant melanoma (MMM) is an aggressive tumour occurring in the upper respiratory tract. It is rare compared to malignant melanoma of the skin. We report a case of a 53-year-old man with left paranasal swelling. A biopsy showed high-grade spindle cell tumour. Subsequently a subtotal maxillectomy was performed. Histopathological examination revealed a hypercellular tumour composed of m...