PURPOSE To evaluate the diagnostic contribution of diffusion-weighted magnetic resonance imaging (MRI) using apparent diffusion coefficient (ADC) values to the characterization of hepatic masses and differentiation of benign and malignant lesions. MATERIALS AND METHODS The study included 30 patients that underwent upper abdominal MRI examinations because of hepatic masses that were found to b...

AIMS To analyse the expression of proteins involved in DNA double strand break detection and repair in the luminal and myoepithelial compartments of benign breast lesions and malignant breast tumours with myoepithelial differentiation. METHODS Expression of the ataxia telangiectasia (ATM) and p53 proteins was immunohistochemically evaluated in 18 benign and malignant myoepithelial tumours of ...

amelanotic melanoma is a variant of malignant melanoma comprising 2% to 8% of all malignant melanomas. the amelanotic presentation of melanoma in the oral cavity is extremely rare and has been reported only occasionally in the literature. moreover, the lack of melanin makes these tumors difficult to diagnose than that of pigmented lesions and the prognosis tends to be poorer. herein, we report ...

Background: Magnetic resonance imaging (MRI) represents the most advanced technique in diagnosis of bone tumors being more sensitive assessing marrow changes and extent compared to CT plain X-ray. The distinction between malignant benign neoplasms is mandatory for appropriate therapeutic choices planning. MRI has upper hand assessment such due its brilliant soft tissue discrimination. use multi...

The aim of this study was to review the efficacy of contrast-enhanced harmonic endoscopic ultrasonography (CH-EUS) in diagnosing gallbladder (GB)-protruded lesions. Thirty-eight patients underwent CH-EUS for the diagnosis of GB-protruded lesions. Twenty-four patients whose major axes of their largest lesions were longer than 10 mm were recruited. The ability of CH-EUS to diagnose malignant or b...

C-myc and c-Ha-ras oncoprotein expression was studied by immunohistochemistry and gene detection by in situ hybridization on serial frozen sections of 32 breast lesions (19 benign biopsies and 13 infiltrating carcinomas). C-myc protein was expressed in 15/19 benign and 12/13 malignant lesions; c-myc gene was detected in 17/19 benign and 13/13 malignant lesions. Although a higher proportion of b...

PURPOSE A newly isolated mediastinal lymph node (LN) or a small pulmonary nodule, which appears during breast cancer surveillance, may pose a diagnostic dilemma with regard to malignancy. We conducted this study to determine which clinical factors were useful for the differentiation of malignant lesions from benign lesions under these circumstances. MATERIALS AND METHODS We enrolled breast ca...

The purpose of this study was to evaluate using lesion washout (WO) volume fraction as a biomarker to improve the characterization of suspicious breast lesions. Study lesions consisted of a total of 60 malignant tumors (BI-RADS 6) and 62 suspicious lesions (BI-RADS 4 or 5). The biopsies of these suspicious lesions resulted in a total of 30 malignant tumors and 32 benign lesions, respectively, y...

BACKGROUND In vivo stains are the prompt resources, which have emerged in recent years to aid as clinical diagnostic tools in detecting early potentially malignant and malignant lesions. Toluidine blue, by its property of retaining in the increased DNA and RNA cellular activity areas, aids in delineating the suspicious areas. However, it is hazardous if swallowed, and has been shown to have tox...