Acanthosis nigricans (AN) is a lesion affecting localized areas of the skin in persons with obesity and/or hyperinsulinemia. Biochemical mechanisms responsible for developing this hyperplastic lesion are unclear, but likely involve local cutaneous growth factors. It is associated with obesity, endocrinopathies (insulin resistance, diabetes mellitus, Cushing disease and acromegaly) and visceral ...

Acanthosis nigricans (AN) is a readily recognizable dermatological manifestation of an underlying metabolic defect like insulin resistance (IR) or obesity which is closely associated with polycystic ovarian syndrome (PCOS). The aim of the study was to compare the clinical and biochemical parameters of Indian adolescent girls with PCOS with and without AN. 58 adolescent girls in the age group of...

Acanthosis nigricans (AN) is a hyperpigmented keratotic skin lesion known to be associated with malignant disease and endocrinopathy. We report a very rare case of generalized AN with Sjögren's syndrome- and systemic lupus erythematosus-like features but without type B insulin resistance. Neither internal malignancy nor other endocrinological disorders, including glucose intolerance, were detec...

1. Subhadarshani S, Singh A, Ramteke PP, Verma KK. Idiopathic eruptive macular pigmentation in an Indian male. Indian Dermatol Online J 2018;8:367‐70. 2. Joshi R. Idiopathic eruptive macular pigmentation with papillomatosis: Report of nine cases. Indian J Dermatol Venereol Leprol 2007;73:402‐5. 3. Joshi R, Palwade PK. Idiopathic eruptive macular pigmentation or acanthosis nigricans? Indian J De...

Obesity in adolescence is a public health priority because it usually tracks into adulthood, resulting in enormous medical and social costs. This underscores the importance of early identification and intervention. Acanthosis nigricans (AN) was once considered a rare paraneoplastic dermatosis, but is now frequently observed in obese adolescents. Current understanding suggests that it is associa...

Acanthosis nigricans is characterised by hyperpigmentation and velvet like thickening of skin. It seen symmetrically involving the neck, axilla, groins, antecubital popliteal fossae, umbilical, perianal areas in advanced conditions, even dorsum hands fingers. To evaluate clinical features epidemiological factors acanthosis pre primary school children to association with body mass index, waist c...