A two-month-old male infant presented with history of respiratory difficulty and got admitted provisional diagnosis pneumonia. On examination patient was having unilateral nasal hypoplasia cyanosis echocardiography showing truncus arteriosus. Detail revealed that mother had valve replacement she taking warfarin during pregnancy. After initial management referred to pediatric cardiac surgery pla...

BACKGROUND Studies on contraceptive use by patients with substance use disorders (SUD) show a concerning low use of contraception. Mainly conducted in USA, they could be irrelevant to patients attending European SUD treatment centers, especially since these studies mostly investigate women suffering from social exclusion, severe material deprivation andopiates use with frequent high-risk drug u...

BACKGROUND Intimate partner violence (IPV) is an important global public health problem. While there is a growing literature on the association between IPV and women's reproductive health (RH) outcomes, most studies are cross-sectional-which weakens inference about the causal effect of IPV on women's RH. This systematic review synthesizes existing evidence from the strongest study designs to es...

objective: to ascertain the utilization of the emergency contraception and to evaluate the impact of intervention on acceptability and utilization of emergency contraceptive pills. materials and methods: this community based cross sectional study was carried out by the department of community medicine in the slums of chandigarh. the study sample was chosen by two stage systematic sampling. part...

BACKGROUND Zambia experiences high unmet need for family planning and high rates of HIV, particularly among youth. While male condoms are widely available and 95% of adults have heard of them, self-reported use in the past 12 months is low among young adults (45%). This study describes factors associated with non-use of male condoms among urban young adults in Zambia. METHODS A household cros...

Therapeutic targets for male contraception are associated with numerous problems due to their focus on disrupting spermatogenesis or hormonal mechanisms to produce dysfunctional sperm. Here we describe the dual genetic deletion of α1A-adrenergic G protein-coupled receptors (adrenoceptors) and P2X1-purinoceptor ligand gated ion channels in male mice, thereby blocking sympathetically mediated spe...