BACKGROUND One of the most important enzymatic disorders that interact with malaria is deficiency of G6PD (Gloucose-6-phosphate dehydrogenase). This enzyme protects red blood cells from hydrogen peroxide and other oxidative damages. Distribution of this enzyme deficiency usually accompanies with low level distribution of malaria disease in most malarious areas. So this hypothesis may be conside...

CONTEXT Malaria accounts for 1-3 million deaths yearly worldwide, mostly in children under 5 years of age in sub-Saharan Africa. Laboratory and clinical studies show an association between acute malaria and a decreased response to diphtheria and tetanus toxoids and to meningococcal, salmonella, and Haemophilus influenzae type b vaccinations. Malaria treatment, chemoprophylaxis, or other forms o...

Understanding exactly when, where and how hosts become infected with parasites is critical to understanding host-parasite co-evolution in natural populations. However, for host-parasite systems in which hosts or parasites are mobile, for example in vector-borne diseases, the spatial location of infection and the relative importance of parasite exposure at successive host life-history stages are...

Background. Malaria is a major public health problem in Ethiopia where an estimated 68% of the population lives in malarious areas. Studying its prevalence is necessary to implement effective control measures. Therefore, the aim of this study was to determine seven-year slide positive rate of malaria. Methods. A retrospective study was conducted at Metema Hospital from September 2006 to August ...

BACKGROUND Malaria is still a public health problem in the world. One of the main objectives of World Health organization is capacity building of authorities who are involved with malaria control activities. METHODS The first course was conducted in 1996 in Bandar Abbas Training center. The course was conducted jointly by the Ministry of Health and Medical Education of Iran, WHO-EMRO and Scho...

days. What is this "terrible disease" that is cured so easily and safely with quinine? "true cases of insolation"? JSo, I say, most assuredly no-, hundreds upon hundreds of Europeans, Military and Civilian, in India, have lost their lives from this " terrible disease" in the past, and many do now, annually, for want of the great antidote, whose value and power is not known to the mass, even of ...

It is a common belief that malaria is the leading health menace of the tropics. Brazil lies for the most part between 40 N. and 300 S., and in many areas is highly malarious. Stitt declares that malaria is the most prevalent and most serious disease of Amazonia and that the lower Rio Branco is probably one of the worst malarial regions in the world. Davis found that the highest rates of malaria...

In tropical areas, where unsupervised use of antimalarial drugs is common, patients with an illness consistent clinically with severe malaria but with negative blood smears pose a management dilemma. Malaria pigment is evident in peripheral blood leukocytes in greater than 90% of patients with severe malaria. To characterize the clearance kinetics of parasitized erythrocytes and malaria pigment...

The second half of the third decade (1990-1995) after the establishment of the Army Malaria Research Unit was characterised by substantial progress in meeting the challenges posed by drug-resistant malaria. In view of the rapid emergence of drug resistance, laboratory/field studies were carried out to develop novel and improved methods to assess and monitor changes in patterns of parasite susce...

Fifty years after narrowly missing the opportunity to eliminate malaria from Sri Lanka in the 1960s, the country has now interrupted malaria transmission and sustained this interruption for more than 12 months - no indigenous malaria cases have been reported since October 2012. This was achieved through a period overlapping with a 30-year separatist war in areas that were endemic for malaria. T...