BACKGROUND A better understanding of case management practices is required to improve inpatient pediatric care in resource-limited settings. Here we utilize data from a unique health facility-based surveillance system at six Ugandan hospitals to evaluate the quality of pediatric case management and the factors associated with appropriate care. METHODS All children up to the age of 14 years ad...

0108 M alaria kills over one million people in Africa each year and contributes 10% of the continent's burden of disease [1]. One of the factors that affects the morbidity and mortality rate is incorrect diagnosis [2]. In this article, we describe a freely available online training tool for health professionals to learn malaria diagnosis. We describe why we launched it and discuss how it is bei...

Though preventable, malaria is still one of the major public health problems worldwidemostly in low and middle income countries (1-4). In 2013, malaria killed over a billion people, mostly in sub-Saharan Africa (5). In 2015, there were over 200 million new cases and more than 400,000 malaria-related deaths around the globe (4). Over three-quarter of the Ethiopian territory is malarious indicati...

BACKGROUND In moving toward malaria elimination, one strategy is to implement an active surveillance system for effective case management. Thailand has developed and implemented the electronic Malaria Information System (eMIS) capturing individualized electronic records of suspected or confirmed malaria cases. OBJECTIVE The main purpose of this study was to determine how well the eMIS improve...

Natural product-derived drugs exemplified by quinine, isolated from South American Cinchona species and artemisinin discovered in China are of immense importance for the treatment of malaria. Although malaria parasites resistant to artemisinin have not yet been found in malaria patients, the need for new antimalarial agents remains. The burden of malaria is heaviest in Africa where over a milli...

Sickle cell disease (SCD) is associated with an increased risk of medical complications during pregnancy. In sub-Saharan Africa, fetal and maternal mortality rates are particularly high. This study evaluated the effect of an active prenatal management program on pregnancy outcome in patients with SCD in an African setting. Pregnant women with SCD attending the National Teaching Hospital in Coto...

BACKGROUND WHO recommends prompt diagnosis and quinine plus clindamycin for treatment of uncomplicated malaria in the first trimester and artemisinin-based combination therapies in subsequent trimesters. We undertook a systematic review of women's access to and healthcare provider adherence to WHO case management policy for malaria in pregnant women. METHODS AND FINDINGS We searched the Malar...

• To develop sustainable malaria research capacity in Africa through international and Pan-African scientific partnerships. Further development of human resources and institutional capacity in Africa is essential to enhance the ability of African countries to address their own health problems. The MIM aims to publicize existing training opportunities and develop research capacity further by fac...

Malaria and poverty are intimately connected. As Nobel Laureate in Medicine T.H. Weller (1958: 497) noted, “It has long been recognized that a malarious community is an impoverished community.” Weller could have said the same for malarious countries. Malaria is most intractable for countries in the poorest continent, Africa. The only parts of Africa free of malaria are the northern and southern...