Radiative colitis is an enteropathy syndrome that may develop after radiation therapy to the abdomen or pelvis. Radiation therapy is a treatment option for cancers in that area. Symptoms start weeks to years after initial radiation dose and include diarrhea, malabsorption, abdominal pain, and nausea. Therapy involves treating symptoms and allowing the bowels to heal. In severe cases partial col...

Background Transthyretin related familial amyloidotic polyneuropathy (TTR-FAP) is an inherited form of amyloidosis, leading to death in about 10 years in most cases for cardiac failure or wasting syndrome. Previous study showed that modified body mass index (mBMI) was related to time before death, duration of gastrointestinal disturbances, malabsorption and functional capacity. Futhermore, outc...

An infant with chronic cytomegalovirus hepatitis and a child with atypical Alagille's syndrome had vitamin D deficiency rickets due to malabsorption. Both received ultraviolet irradiation. This treatment corrected biochemical abnormalities and healed the rickets. In the infant use of a sunlamp at home maintained normal 25 hydroxy-vitamin D for over a year. Our study shows that ultraviolet irrad...

Imerslund-Gräsbeck syndrome (IGS) or selective vitamin B(12) (cobalamin) malabsorption with proteinuria is a rare autosomal recessive disorder characterized by vitamin B(12) deficiency commonly resulting in megaloblastic anemia, which is responsive to parenteral vitamin B(12) therapy and appears in childhood. Other manifestations include failure to thrive and grow, infections and neurological d...

The current policy in this department is to utilize small intestinal biopsy early in the course of investigation of children with suspected malabsorption (Townley, 1971). Also, we have not been unduly hesitant to perform intestinal biopsy in research studies, after the procedure and its risks have been explained to parents (Barnes and Townley, 1973). Others have raised doubts about the safety (...

Malabsorption of oral antimycobacterial drugs is a rare cause of treatment failure in tuberculosis (TB). Several predisposing comorbidities have been recognised. HIV infection is the most important risk factor referred in the literature. There are few reports about antimycobacterial drugs malabsorption, particularly in the absence of predisposing comorbidities. The authors present a clinical ca...