High-grade meningiomas are rare extra-axial tumors, frequently causing brain invasion and prominent brain edema. Patients harboring high-grade meningiomas occasionally present with behavior changes. Data about frequency and prognostic importance of preoperative behavior changes in patients with high-grade meningiomas is missing. 86 patients with primary high-grade meningiomas were analyzed. Sta...

Intradural metastatic tumors of the foramen magnum region are extremely rare tumors. We report a 73-year-old patient that presented with right hemiparesis and a recent history of prostate biopsy for an enlarged prostate. Imaging revealed an anterolateral intradural foramen magnum mass with compression of the medulla. A right far lateral approach with condyle preservation was used to resect the ...

Meningiomas are the most common benign intracranial neoplasms. Nearly 20% of all primary intracranial tumors are meningiomas. Primary intraosseous meningiomas are a subtype of the meningiomas that represents the most uncommon manifestation of meningiomas. Although rare, these tumors can be found to occur in unexpected areas of the head and neck. The patient was a 78- year-old male who was opera...

Surgical resection is the treatment of choice for most intracranial meningiomas. We review the current state of adjuvant therapies, including radiation and chemotherapy. Conventional external beam radiation and stereotactic radiosurgery remain second-line options for patients unwilling or unable to undergo surgery. Radiation therapy is most useful in the setting of recurrent or residual tumor a...

Histopathological examination and grading of meningiomas gives valuable prognostic information, although the method is subject for interobserver variability. The aim of this study was to review a large series of human meningiomas in order to examine the frequency of benign (grade I), atypical (grade II), and anaplastic (grade III) forms depending on various WHO classification schemes. In additi...

The role of radiation in the induction of central nervous system tumours has repeatedly been documented. Meningiomas induced by low doses of cranial irradiation have been described in many series of cases, but meningiomas induced by high doses of irradiation have still been reported in a limited number of cases. We report the case of a 25-year-old man who presented multiple meningiomas and who ...

The purpose of the present study was to examine growth hormone receptor (GHR) gene expression by real-time PCR and demonstrate immunocytochemically the localization of GHR in four chicken oviductal parts, i.e. infundibulum, magnum, isthmus and shell gland. Experiments were carried out on Hy-Line laying hens decapitated 2 h after oviposition. GHR mRNA was expressed in all examined oviductal segm...

This study was intended to investigate some aspects of the morphometric characteristics of the neurocranium in domestic cat (Felis catus) of Bangladesh. Twenty adult domestic cat including 10 males and 10 female were euthanized using diazepam (@ 20 mg/kg) and their skulls were macerated to give morphometric parameters. Student t-test with level of significance set at 5% (p < 0.05) was used to a...

BACKGROUND Achondroplasia is a relatively frequent genetic disorder that may lead to limb weakness, motor-mental retardation, hydrocephaly, and respiratory disorders. In this pathology, foramen magnum stenosis and accompanying disorders like respiratory depression is well documented. CASE PRESENTATION A 2.5 year-old child with the diagnosis of achondroplasia admitted to our clinic with severe...