1. Magnesium metabolism has been studied in forty-eight patients with primary hyperparathyroidism. Metabolic balance studies were undertaken in forty-three untreated patients and in fifteen patients after parathyroidectomy. The data obtained are compared with the pattern of magnesium metabolism in healthy adults, as established by analysis of collected nutritional studies. The renal handling of...

Magnesium is an important cofactor for many biological processes, such as protein synthesis, nucleic acid stability, or neuromuscular excitability. Extracellular magnesium concentration is tightly regulated by the extent of intestinal absorption and renal excretion. Despite the critical role of magnesium handling, the exact mechanisms mediating transepithelial transport remained obscure. In the...

The effects of intravenous magnesium on exercise-induced angina were examined in 15 patients with variant angina and in 13 patients with stable effort angina and were compared with those of placebo. Symptom-limited bicycle exercise and thallium-201 myocardial scintigraphy were performed after intravenous administration of 0.27 mmol/kg body weight of magnesium sulfate and after placebo on differ...

In comparison with calcium, magnesium is an "orphan nutrient" that has been studied considerably less heavily. Low magnesium intakes and blood levels have been associated with type 2 diabetes, metabolic syndrome, elevated C-reactive protein, hypertension, atherosclerotic vascular disease, sudden cardiac death, osteoporosis, migraine headache, asthma, and colon cancer. Almost half (48%) of the U...

Clinical and experimental evidence indicates alcohol consumption as one of the major causes of magnesium loss from several tissues. As a result of this loss, serum magnesium tends to decrease while urinary magnesium excretion increases 2-3 fold. Experimental data confirm that chronic consumption of 6% ethanol in the Lieber De-Carli diet for 3 weeks results in a marked decrease in total tissue m...

Thirty-six crossbred gilts 10 months of age were bred and assigned to dietary magnesium levels of 400 or 900 ppm. At parturit ion the levels were modified to 150 and 650 ppm. During lactation phosphorus levels of .30 or .54% were fed within each magnesium level. Magnesium levels did not influence the number or weight of pigs at birth or weaning. Sows fed the high level of magnesium (650 ppm) ma...

1. Larvae of Aedes campestris can survive in water containing up to 100 Mg even though they ingest and absorb into the haemolymph considerable amounts of magnesium-rich fluid. 2. Isolated Malpighian tubules, unlike those of Rhodnius and Carausius secreted fluid containing elevated concentrations of magnesium. This transport displayed saturation kinetics, the half-maximal rate being at approxima...

HE BIOLOGICAL n#{248}ui of magnesium is of considerable importance in the processes of synthesis in the organic world. According to the work of Academician V. I. Vernadskii, chlorophyll contains up to 0.2 per cent magnesium. Magnesium enters into the composition of proteins, of plasma, and of the basic colloids of the living body. The magnesium in living matter constitutes n.10_2 of its weight....

Serial nerve conduction velocities in the peroneal and ulnar nerves have been measured in 10 patients on regular dialysis treatment over a three year period. Each patient alternated between phases on dialysis with magnesium-containing dialysate (1·5-1·7 m-equiv/l.) and phases on `magnesium-free' dialysate (0·2 m-equiv/l.). Plasma magnesium concentrations were high both pre- and post-dialysis du...

Magnesium deficiency in pregnancy frequently occurs because of inadequate or low intake of magnesium. Magnesium deficiency during pregnancy can induce not only maternal and fetal nutritional problems, but also consequences that might last in offspring throughout life. Many epidemiological studies have disclosed that small for gestational age (SGA) is associated with an increased risk of insulin...