Wilson disease is an autosomal recessive copper storage disease resulting from an inability of the liver to excrete copper. Patients can present at a young age, generally with symptoms of liver copper intoxication, or later on, generally with neurological symptoms. The gene for Wilson disease has recently been cloned. Five mutations have been described so far, but only one is found frequently, ...

BACKGROUND Although many studies have modelled the national burdens of hospitalizations and deaths due to influenza, few studies have considered the outpatient burden. To fill this gap for the United States (US), we applied traditional statistical modelling approaches to time series derived from large medical claims databases held in the private sector. METHODS We accessed ICD-9-coded office ...

Abstract How does teacher–child interaction quality in early child care and education settings influence the development of social-emotional skills children at around two to three years age? We measured interactions on side teachers ( N = 9, CLASS Toddler) assessed self-regulatory through an individual assessment (i.e. working memory by “Hidden Toys Task”, selective attention with NEPSY, inhibi...

OBJECTIVES Present research aimed to explore relationship between cognitive failure, teacher's rejection (TR), interpersonal relationship anxiety (IRA) and Signs of Dyslexia (SD) in children with dyslexia. Another aim was to explore TR, SD and IRA as predictors of cognitive failure and final aim was to see TR, SD and cognitive failure as predictors of IRA. METHOD Sample included140 students (...

Aim: To measure and compare the body mass index (BMI) inwomen diagnosed with endometriosis with healthy females. Design: Descriptive comparative study Patients: Fifty women, age 20-40 years, diagnosed with endometriosis were included. Methods: A total of 100 women were included in the study. The study population was divided into two groups endometriosis group (n=50) and control group (n=50). Th...

Purpose: Prim ary lung tum ors in children and adolescents are uncom m on. We report here on the clinical presentations, the m ethods of treatm ent, the results and the outcom es of a series of children w ith these rare tum ors. Materials and Methods: We conducted a retrospective review on all the patients less than 19 years of age w ith prim ary lung tum ors and who were treated at Samsung Med...

Recent studies have suggested that classical conditioning may be capable of modulating early sensory processing in the human brain, and that there may be differences in the magnitude of the conditioned changes for individuals with major depressive disorder. The effect of conditioning on the N170 event-related potential was investigated using neutral faces as conditioned stimuli (CS+) and emotio...

BACKGROUND Non-sustained ventricular tachycardia (NSVT) during ambulatory electrocardiographic monitoring (typically occurring at rest or during sleep) is associated with an increased risk of sudden cardiac death in patients with hypertrophic cardiomyopathy. The prevalence and prognostic significance of ventricular arrhythmias during exercise is unknown. METHODS AND RESULTS This was a cohort ...

AIMS This preliminary randomized, parallel-group comparative study evaluated the efficacy of ipragliflozin for reduction of small dense low-density lipoprotein cholesterol (sd LDL-C) levels in Japanese patients with type 2 diabetes mellitus (T2DM). METHODS Sixty-two patients with T2DM (age, 56 ± 8 years; hemoglobin A1c levels, 8.1 ± 0.9%; BMI, 27.5 ± 3.3 kg/m2) were randomly assigned in a 2:1...

OBJECTIVE To calculate the best possible estimates for age specific life expectancy (LE) and anticipated age at the time of death (AAD) in patients with Parkinson's disease (PD) compared with the general population in the UK. These may be of greater value to patients than standardised mortality ratios (SMRs), which are usually reported in studies on mortality in PD. METHODS A literature revie...