We observed 276 HIV-infected patients to determine the frequency, degree, and clinical presentation ofthe lymphocytic alveolitis in different stages of H1V disease, and also to identify the lymphocyte subsets involved. In 154 patients with proved lung infections or tumors (group A), bronchoalveolar lavage fluid showed lymphocytosis in 78 percent of cases. In 122 subjects (31 AIDS and 91 IIIV-in...

Lymphocytic hypophysitis is a rare inflammatory lesion of the pituitary gland. The disease shows a striking female predilection of approximately 9:1 and commonly affects young women during late pregnancy or in the postpartum period. Clinical presentation and radiological findings may mimic pituitary adenoma. We have reviewed the literature and report two cases of lymphocytic hypophysitis, neith...

A 25 year old non-pregnant woman presented with a one-year history of amenorrhoea and polyuria. Three months before her admission, she had suffered lymphocytic meningitis. Hormonal studies revealed hypopituitarism and central diabetes insipidus, with associated primary autoimmune hypothyroidism. Computed tomographic scan and magnetic resonance imaging showed a pituitary mass with suprasellar ex...

Systemic mastocytosis with associated clonal haematological non-mast cell lineage disease (SM-AHNMD) is a heterogeneous group of mast cell disorders with different clinical, pathologic and underlying molecular characteristics. While myelomonocytic/myeloid neoplasia overwhelmingly predominates the AHNMD component, lymphoproliferative disorders rarely occur as an AHNMD component of SM-AHNMD. Here...

Leukocytes express a major sialoglycoprotein, leukosialin, of which the apparent molecular weight (mol wt) can be variable according to the differences in 0-glycans attached to this molecule. In the present study, we analyzed the structures of 0-glycans attached to leukosialin present in various T-lymphocytic leukemia cells. T-lymphoid cells from patients with acute T-lymphocytic leukemia expre...

Chronic lymphocytic leukemia/small lymphoma (CLL/SLL) is an indolent small B-cell neoplasm that may transform into a clinically aggressive disease, namely Richter syndrome, usually as diffuse large lymphoma. Besides, CLL/SLL encompasses increased risk of developing other secondary cancers, including variety T-cell lymphomas, often the anaplastic large-cell type or with cytotoxic phenotype. Here...