Background. Tanzania started a countrywide lymphatic filariasis elimination programme in 2000 adopting the mass drug administration (MDA) strategy. The drug used for the programme was the combination of ivermectin and albendazole. However, there is limited information on the current epidemiological trend of the infections, where MDA implementation is ongoing. The present study aimed at assessin...

1.1 Pathogenesis of elephantiasis, and historical controversy as to on the role of bacterial infection Elephantiasis occurs in the chronic stage of lymphatic filariasis due to the obstruction of lymphatic vessels by filariae. After invasion into lymph vessels, third stage larvae grow to maturity in the lymphatic system, mainly in and around the genitourinary system. Amaral et al. (1994) [1] obs...

.In this review, the mosquito vector borne diseases (VBD) majorly malaria, dengue, filariasis, chikungunya, Japanese encephalitis, Zika were presented to comprehend global disease incidence as control of these transmitting vectors are challengeable globally nowadays. It has been found that malaria affects nearly 500 million people and lymphatic filariasis about 100 worldwide every year. About 2...

Filariasis is a disabling parasitic disease and it constitutes as a major health problem in most of the tropical and sub-tropical countries. One hundred and twenty million people in at least 80 tropical and sub-tropical countries are infected with lymphatic filarial parasite, with one billion people being at risk of the disease. The laboratory diagnosis of filariasis is conventionally made by d...

Although lymphatic filariasis is known to have been endemic in Haiti since at least the mid 1700s, a national filariasis survey has never been conducted. As a first step in the national program to eliminate filariasis, we collected blood in January-April 2001 from 50-250 school children (6-11 years old) in all 133 communes of the country using an adaptation of the lot quality assurance sampling...

Mass drug administration (MDA) programs have achieved remarkable success in limiting the pathology and transmission of the human parasitic infections onchocerciasis and lymphatic filariasis. The full implementation of MDA campaigns for filariasis elimination has been stymied by the unacceptable incidence of severe adverse events observed following drug treatment of a subset of individuals who h...

Human filariasis is mainly caused by the parasites, Wuchereria bancrofti and Brugia malayi, whose adults live in the lymphatic vessels of humans. In Japan, bancroftian filariasis was once endemic, but has been completely eradicated from the country. Although imported cases of filariasis are occasionally reported [1,2,3], no autochthonous case has been identified in recent years. By contrast, mo...

BACKGROUND The prevalence of Wuchereria bancrofti, which causes lymphatic filariasis (LF) in The Gambia was among the highest in Africa in the 1950s. However, surveys conducted in 1975 and 1976 revealed a dramatic decline in LF endemicity in the absence of mass drug administration (MDA). The decline in prevalence was partly attributed to a significant reduction in mosquito density through the w...

Lymphatic filariasis (LF) is still a major public health problem. The disease is ranked by the World Health Organization (WHO) as the second leading cause of permanent and long-term disability, and has been targeted for elimination by 2020. Effective diagnosis LF is required for treatment of infected individuals, for epidemiological assessment and for monitoring of the control program. Conventi...