UNLABELLED Lymph node metastasis is the major clinicopathologic feature associated with poor prognosis in patients with head and neck squamous cell carcinoma (HNSCC). Here, web-based bioinformatics meta-analysis was performed to elucidate the molecular mechanism of lymph node metastasis of human HNSCC. Preferential upregulation of Myosin 1b (MYO1B) transcript in HNSCC datasets was identified. M...

Abstract Colorectal cancer (CRC) is the fourth most common in men and third women worldwide. The incidence mortality of CRC was increasing rapidly China. Lymph node-negative colorectal patients with synchronous liver metastasis (LNLM1) defined as “skip” lymph vascular invasion on hepatic metastasis, who presenting poor prognosis. We aiming to investigate potential mechanism for cancer. microarr...

The frequency and pattern of lymph node metastasis and the extent of dissection for isthmic papillary thyroid carcinoma (PTC) remain unclear, and the aim of this present study was to evaluate these characteristics and to attempt to detect the best surgical protocol for isthmic PTCs. A total of 3185 consecutive patients with PTCs were reviewed. Of these patients, 47 with a single isthmic PTC wer...

OBJECTIVES Sentinel lymph node biopsy has been introduced for head and neck cancer with promising results. Research in breast cancer has revealed different histopathological features of occult lymph node metastasis with possibly different clinical and prognostic implications. The aim of the study was to evaluate the histopathological features of occult metastasis detected by sentinel lymph node...

lymph node (ln) metastasis is considered an important prognostic factor in patients with prostate cancer. the aim of this study was to determine the rate of ln metastasis among an iranian population who underwent radical prostatectomy (rp) with pelvic ln dissection (plnd). in a retrospective review of medical records, 450 rp cases were included and the data on ln metastasis were extracted from ...

OBJECTIVE Breast cancer metastasis to the lung is common. The resection of lung metastases in patients with breast cancer has been controversial. Here, we present a very rare case of pulmonary and mediastinal lymph node metastases in a patient with breast cancer who had a disease-free interval (DFI) of more than 33 years. METHODS An involved lobectomy and systematic mediastinal lymph node dis...

Solitary metastasis of renal cell carcinoma (RCC) in the mediastinal lymph nodes is rare in patients without lung metastasis. We herein report a case of RCC with solitary mediastinal lymph node metastasis. A mass in the anterior mediastinum was found in the chest computed tomography (CT) scan of an asymptomatic 43-year-old-man. A mass on the right kidney was also revealed in an abdominal CT sca...

A 59 year old man is presented with adenocarcinoma of the stomach. In order to evaluate for the presence of the non-lifting sign, methylene blue was injected 2 mm from the perimeter of the tumor. Since the tumor lifted, snare removal of the tumor was done, safely. Partial gastrectomy was performed 2 weeks after endoscopic removal of the tumor which revealed no residual tumor or lymph node ...

The sites of lymph node metastasis of papillary thyroid carcinomas are typically the paratracheal and jugular lymph nodes. On the other hand, metastasis to the retropharyngeal or parapharyngeal nodes from papillary thyroid carcinomas is very rare. During the last two decades, limited to cases with a histologically definite diagnosis by surgery, only 39 cases have been reported. All reported cas...

PURPOSE To investigate the correlated factors for lymph node metastasis and prognosis for patients with T2 gastric cancer. METHODS A total of 442 patients with T2 gastric cancer who underwent gastrectomy from January 1996 to December 2009 were evaluated. The clinicopathological parameters were analyzed for lymph node metastasis and prognosis, including gender, age, tumor size, tumor location,...