نتایج جستجو برای: lupus nephriti s

تعداد نتایج: 751321  

Journal: : 2021

Výskyt ANCA protilátek bývá u pacientů se systémovým lupus erytematodes (SLE) popisován asi ve 24-31 % případů, nemají však vztah k distribuci a tíži orgánového postižení SLE jejich rutinní monitoring nedoporučuje. Overlap syndrom systémového s asociovanou vaskulitidou (AAV) zcela vzácně, následující kazuistika pacientky těžkým postižením ledvin v rámci AAV pou...

JH Shariati S.A GHasemi

Nocardiosis is a rare infection that in more frequent in patients with systemic lupus Erythematosus and its clinical manifestations are nonspecific.while concurrent treatment by corticosteroids is an independent risk factor for nocardiosis it increases both diagnostic and mangement problems.this article presents a 35 years old woman who has systemic lupus Erythematosus.she was hospitalized due ...

Background: Systemic lupus erythematous is an autoimmune disease associated with atherosclerotic manifestations or metabolic disturbance due to inflammation. The aim of this study was to determine frequency of metabolic syndrome (MetS) in SLE compared to healthy controls. Methods: In this cross-sectional study, 150 SLE patients and 220 healthy volunteers were enrolled. MetS was diagnosed acc...

Journal: :International Journal of Health Research and Medico Legal Practice 2020

2014
Mircea Niculae Penescu Corina-Daniela Ene (Nicolae) Emanoil Ceauşu Ilinca Nicolae

Methods Serum level of GSTpi was quantified by immunoenzymatic method in 42 patients with active systemic lupus erythematous (based on SLEDAI score), without any treatment divided in two groups: Group A – 30 cases with active SLE (SLEDAI = 11.2 ± 3.2), with chronic C hepatitis; Group B – 12 cases with active SLE (SLEDAI = 12.1 ± 4.5) without hepatitis C. The results were compared to those obtai...

2013
Dipak R Patel Bruce C Richardson

Systemic lupus erythematosus is a chronic relapsing autoimmune disease that primarily afflicts women, and both a genetic predisposition and appropriate environmental exposures are required for lupus to develop and flare. The genetic requirement is evidenced by an increased concordance in identical twins and by the validation of at least 35 single-nucleotide polymorphisms predisposing patients t...

Journal: :Journal of the American Society of Nephrology : JASN 2014
Sharon A Chung Elizabeth E Brown Adrienne H Williams Paula S Ramos Celine C Berthier Tushar Bhangale Marta E Alarcon-Riquelme Timothy W Behrens Lindsey A Criswell Deborah Cunninghame Graham F Yesim Demirci Jeffrey C Edberg Patrick M Gaffney John B Harley Chaim O Jacob M Ilyas Kamboh Jennifer A Kelly Susan Manzi Kathy L Moser-Sivils Laurie P Russell Michelle Petri Betty P Tsao Tim J Vyse Raphael Zidovetzki Matthias Kretzler Robert P Kimberly Barry I Freedman Robert R Graham Carl D Langefeld

Lupus nephritis is a manifestation of SLE resulting from glomerular immune complex deposition and inflammation. Lupus nephritis demonstrates familial aggregation and accounts for significant morbidity and mortality. We completed a meta-analysis of three genome-wide association studies of SLE to identify lupus nephritis-predisposing loci. Through genotyping and imputation, >1.6 million markers w...

2017
Sonia Jain Anjali Bose Banajit Bastia Hritika Sharma Ruchi Sachdeva Arun K. Jain Rahul Pal

Hemolysis-associated anemia is characteristic of diseases such as atherosclerosis, lupus, malaria, and leishmaniasis; the toxic effects of free hemoglobin (Hb) have been extensively described. This study was based on the premise that release of this sequestered, inflammatory molecule can result in deleterious immunological consequences, particularly in the context of pre-existing lupus. IgG ant...

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