Alveolar capillary dysplasia with misalignment of pulmonary veins (ACD/MPV) is a rare, fatal developmental lung disorder of neonates and infants, associated with severe persistent pulmonary hypertension unresponsive to treatment. We reported the case of a term newborn with delayed presentation of ACD/MPV and a novel mutation of FOXF1 gene that received supportive cardiopulmonary treatments, inh...

Surgical correction of congenital cardiac malformations or aortocoronary bypass surgery in many cases implies the use of cardiopulmonary-bypass (CPB). However, a possible negative impact of CPB on internal organs such as brain, kidney, lung and liver cannot be neglected. In general, CPB initiates a systemic inflammatory response (SIRS) which is presumably caused by contact of blood components w...

lung exposure to sulfur mustard (sm) results in pulmonary complications, which is the main cause of long-term disability and morbidity. up to now, the precise mechanisms of sm-induced lung complications has not been identified. the aim of this study was to evaluate apoptosis in the lung tissue of sm-exposed individuals. the study was performed on archived lung paraffin-embedded tissue specimens...

Background. Arteriovenous malformations of the brain are a rare vascular pathology. Many studies focus on features venous drainage arteriovenous malformations. The angioarchitectural and hemodynamic component can influence patient management. Objective . To evaluate relationship between types clinical course. Design methods. Survey included 61 adult patients neurosurgical department № 3 Polenov...

Failure of development of the primitive lung bud leads to an extremely rare congenital anomaly with a prevalence of 34 per 10 lac live births termed pulmonary aplasia. In half of such cases, associated congenital malformations of the cardiovascular, skeletal, gastrointestinal, or genitourinary systems are present. The Mayer-Rokitansky-Küster-Hauser (MRKH) syndrome is defined as the congenital a...

Pulmonary congenital abnormalities are rare disorders including congenital pulmonary airway malformations (CPAM) and pulmonary sequestration (PS). CPAM is a lesion characterized by the presence of anomalous bronchiolar or acinar structures, variable in size, either cystic or not cystic. PS is generally defined as nonfunctioning lung tissue that is not in normal continuity with the tracheobronch...

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A microscopic study was made of the lungs of 18 patients with congenital malformations of the heart in which there was obstruction of pulmonary venous drainage. Alterations in various components of the pulmonary vascular bed and of the lung parenchyma were described and correlated with the clinical course and the type of malformation present. A quantitative evaluation of the pulmonary arterial ...

The provision of health care for children and adults with complex heart disease has progressed by leaps and bounds in the last 60 years [1]. With developments in perfusion technology and refinement of surgical techniques, most complex heart and lung malformations can be treated adequately. Parallel developments in the field of cardiology such as early diagnosis and rapid stabilization, improvem...

Pulmonary sequestration is a rare congenital anomaly, characterized by nonfunctional embryonic pulmonary tissue. Pulmonary sequestration accounts for 0.15-6.40% of all congenital pulmonary malformations. This anomaly, which is classified as intralobar or extralobar, involves the lung parenchyma and its vascularization. We report the case of a 56-year-old male presenting with hemoptysis. A chest...