The emergent epidemic of metabolic syndrome and its complex list of sequelae mandate a more thorough understanding of benign prostatic hyperplasia and lower urinary tract symptoms (BPH/LUTS) in the context of systemic metabolic disease. Here we discuss the nature and origins of BPH, examine its role as a component of LUTS and review retrospective clinical studies that have drawn associations be...

Lower urinary tract symptoms (LUTS) in men are highly prevalent among those aged >50 yr. Contemporary analyses of claim databases in the Western world have shown that LUTS generate millions of prescriptions and thousands of surgical interventions each year, representing a huge economic burden [1]. Moreover, the field of LUTS management is rapidly evolving due to new drug treatment indications a...

The emergent epidemic of metabolic syndrome and its complex list of sequelae mandate a more thorough understanding of benign prostatic hyperplasia and lower urinary tract symptoms (BPH/LUTS) in the context of systemic metabolic disease. Here we discuss the nature and origins of BPH, examine its role as a component of LUTS and review retrospective clinical studies that have drawn associations be...

The impact of nighttime lower urinary tract symptoms suggestive of benign prostatic hyperplasia (LUTS/BPH) such as nocturia has long been underestimated. Lack of sleep because of these symptoms can considerably affect a patient’s performance and his general feeling of well-being. Chronic sleep deficit may lead to increased morbidity and mortality. Therefore, it is important that therapies for L...

OBJECTIVES Benign prostatic hyperplasia (BPH) is considered a frequent cause of bladder outlet obstruction (BOO) and lower urinary tract symptoms (LUTS), although the physiopathologic mechanism through which BPH causes LUTS is not clear. Several morphologic and functional modifications of the bladder detrusor have been described in patients with BPH and could play a direct role in determining s...

As our population ages, the number of patients presenting to their primary care physicians with urologic problems is significantly increasing. Urologic issues are the third most common type of complaint in patients 65 yr of age or older and account for at least a part of 47% of office visits.1 One of the most predominant urologic problems in elderly persons, and the focus of this chapter, is lo...

Lower urinary tract symptoms (LUTS) are frequently encountered in clinical practice, especially in older men. The main focus in the primary treatment of men with complaints of violation of urination should be paid to assessing their severity on the basis of IPSS questionnaire. It is important to identify the predominant symptoms that determine treatment. In the absence of absolute indications f...

AIMS Lower urinary tract symptoms (LUTS) are common in both men and women, and are among the most prevalent patient complaints heard by primary care physicians (PCPs). This article aims to provide PCPs with a logical algorithm for the assessment and initiation of treatment for LUTS in the male patient. RESULTS Management of LUTS involves a focused history and physical, as well as the assessme...

Evidence to substantiate recommendations for restriction of caffeinated or acidic beverages as self-management for lower urinary tract symptoms (LUTS) is limited. We examined longitudinal and acute associations between beverage intake and LUTS in the Boston Area Community Health (BACH) cohort (n = 4,144) between 2002 and 2010. Multivariable models tested associations between baseline intakes an...

This is the first study to investigate the influence of depression, anxiety and somatization on the treatment response for lower urinary tract symptoms/benign prostatic hyperplasia (LUTS/BPH). The LUTS/BPH patients were evaluated with the Korean versions of the International Prostate Symptom Score (IPSS), the Patient Health Questionnaire-9 (PHQ-9), the 7-item Generalized Anxiety Disorder Scale ...