Although some studies show that the upper esophageal sphincter (UES) contracts during transient lower esophageal sphincter relaxation (TLESR), others show that it relaxes. We hypothesized that the posture of the subject and constituents of gastroesophageal reflux (GER) may determine the type of UES response during the TLESR. High-resolution manometry and esophageal pH/impedance recording were p...

OBJECTIVE The pathophysiological data on Barrett's esophagus are scant in Asia, so the purpose of this study was to compare and analyze the pathophysiological characteristics of Barrett's esophagus and reflux esophagitis among Chinese in Taiwan. PATIENTS AND METHODS From November 2001 to January 2003, fifteen patients with Barrett's esophagus were consecutively enrolled as the Barrett's esoph...

Pehlivanov, Nonko, Jianmin Liu, Tania Arora, Yoshihiro Yamamoto, and Ravinder K. Mittal. Lower esophageal sphincter monitoring with sphinctometer: in vitro and in vivo studies. Am. J. Physiol. 277 (Gastrointest. Liver Physiol. 40): G577–G584, 1999.—The sphinctometer is a solid-state device system for prolonged ambulatory recordings of the lower esophageal sphincter (LES) pressure. The aims of t...

Of 130 patients diagnosed to have esophageal motility disorders, transformation of diffuse esophageal spasm (DES) into achalasia was identified in one patient. The clinical syndmme of DES was first described by Hamilton Osgood in 1889. It is characterizedby symptoms of substernal chest pain and dysphagia, tertiary contractions on barium swallow and a manometric pattern of frequent simultaneous ...

CC This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons. org/licenses/by-nc/3.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. Figure 1. (A) Upper gastrointestinal endoscopic finding shows a concentric ring-like muc...

INTRODUCTION Data regarding the age impact on the clinical presentation and esophageal motility in adults with idiopathic achalasia are scarce. OBJECTIVE To asses the clinical and manometric features of elderly patients with idiopathic achalasia. METHODS The medical charts of 159 patients diagnosed with achalasia were divided into two groups according to the patients' age: ?60 years (n = 12...