نتایج جستجو برای: low molecular weight heparin lmwh

تعداد نتایج: 2019339  

2017
Flávia Dias Xavier Paulo Marcelo Gehm Hoff Maria Ignez Braghiroli Ana Carolina Carvalho Rocha Paterlini Karla Teixeira Souza Luiza Dib Batista Bugiato Faria Fernando Sergio Blumm Ferreira Karime Kalil Machado Gustavo dos Santos Fernandes

BACKGROUND Venous thromboembolic events (VTEs) are common and potentially fatal complications in cancer patients, and they are responsible for the second most common cause of death. Low molecular weight heparin (LMWH) is the gold-standard treatment, but the costs involved limit its use, especially in developing countries. Recently, the oral anticoagulant rivaroxaban, which directly inhibits fac...

Journal: :The Journal of bone and joint surgery. British volume 2005
N Steele R M Dodenhoff A J Ward M H Morse

We prospectively studied the outcome of a protocol of prophylaxis for deep vein thrombosis (DVT) in 103 consecutive patients undergoing surgical stabilisation of pelvic and acetabular fractures. Low-molecular-weight heparin (LMWH) was administered within 24 hours of injury or on achieving haemodynamic stability. Patients were screened for proximal DVT by duplex ultrasonography performed ten to ...

Journal: :Arteriosclerosis, thrombosis, and vascular biology 2005
Marco Presta Pasqua Oreste Giorgio Zoppetti Mirella Belleri Elena Tanghetti Daria Leali Chiara Urbinati Antonella Bugatti Roberto Ronca Stefania Nicoli Emanuela Moroni Helena Stabile Maura Camozzi German Andrés Hernandez Stefania Mitola Patrizia Dell'Era Marco Rusnati Domenico Ribatti

OBJECTIVE Low-molecular-weight heparin (LMWH) exerts antitumor activity in clinical trials. The K5 polysaccharide from Escherichia coli has the same structure as the heparin precursor. Chemical and enzymatic modifications of K5 polysaccharide lead to the production of biotechnological heparin-like compounds. We investigated the fibroblast growth factor-2 (FGF2) antagonist and antiangiogenic act...

Journal: :American journal of physiology. Gastrointestinal and liver physiology 2009
Edward N Harris Bruce A Baggenstoss Paul H Weigel

The human hyaluronic acid (HA) receptor for endocytosis (HARE/stabilin-2) is the primary clearance receptor for systemic HA, chondroitin sulfates, and heparin, but not for heparan sulfate or keratan sulfate (Harris EN, Weigel JA, Weigel PH. J Biol Chem 283: 17341-17350, 2008). HARE is expressed in the sinusoidal endothelial cells (SECs) of liver and lymph nodes where it acts as a scavenger for ...

Journal: :Pharmacotherapy 2004
Edith A Nutescu Cathy M Helgason

Anticoagulation is an essential component of the care of patients with venous thromboembolism (VTE). Traditional anticoagulants for the treatment of VTE include unfractionated heparin (UFH), low-molecular-weight heparin (LMWH), and the oral vitamin K antagonist, warfarin. A variety of anticoagulant agents with improved pharmacologic and clinical profiles are emerging and offer benefits over the...

2011
Ali Zalpour Michael H. Kroll Vahid Afshar-Kharghan Syed Wamique Yusuf Carmen Escalante

The association between cancer and venous thromboembolism (VTE) has been well documented in the literature. Prevention and treatment of VTE in cancer patients is imperative. Typically, the mainstay regimen for VTE prevention and treatment has been anticoagulation therapy, unless contraindicated. This therapy consists of unfractionated heparin (UFH), low-molecular-weight heparin (LMWH), factor X...

Journal: :Medicinski Glasnik Specijalne Bolnice za Bolesti Štitaste Žlezde i Bolesti Metabolizma Zlatibor 2022

Elderly patients with a hip fracture are at significantly higher risk for developing venous thromboembolism (VTE). The incidence of fatal pulmonary embolism (PE) occurs in 2-3% after elective and knee surgery about 6-7% surgery, men (10,2%) than women (4,7%). use pharmacological prophylaxis reduces the symptomatic VTE. Pharmacological includes antiplatelet drugs (aspirin), unfractionated hepari...

2014
Ilaria Pagnini Gabriele Simonini Loredana Cavalli Giancarlo la Marca Annamaria Iuliano Maria Luisa Brandi Francesca Bellisai Bruno Frediani Mauro Galeazzi Luca Cantarini Rolando Cimaz

BACKGROUND To evaluate bone status in children born from mothers followed for autoimmune diseases and treated during pregnancy with low molecular weight heparin (LMVH) and/or prednisone. FINDINGS History, physical examination, laboratory tests and phalangeal ultrasonography were performed. Demographic, clinical, and laboratory data were entered into a customized database, and results were ana...

2005
Ajay K. Kakkar

22 Cancer Control acteristics (eg,enhanced angiogenesis or tumor growth). In other words, the development of thrombosis may be indicative of an activated coagulation system that is affecting the tumor itself. To that end, it is possible that anticoagulants may play a role in affecting the outcomes in cancer patients and that low-molecular-weight heparin (LMWH) may influence survival in patients...

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