osteoid osteoma is a benign bone tumor that rarely involves joints. although there are several reports of arthroscopic osteoid osteoma excisions, to our knowledge, there are no reports of this type of treatment for osteoid osteoma in carpal bones. we report two cases of arthroscopic (a person who had a pain in the left wrist and the other one with carpal tunnel syndrome) with excision of osteoi...

osteogenesis imperfecta is a rare inherited connective tissue disorder with an expression that varies from mild to severe disease affecting bone, sclera and middle ear. fertility is preserved, especially in those patients with type 1. we present hereby a pregnant woman with osteogenesis imperfecta that had over 30 fractures in long bones and vertebrae. the object of this report was to determine...

This study was to evaluate the age-dependent effects of caffeine exposure on the long bones and reproductive organs using male rats. A total of 15 immature male rats and 15 young adult male rats were allocated randomly to three groups: a control group and two groups fed caffeine with 120 and 180 mg/kg/day for 4 weeks. Exposure to caffeine at either dose significantly reduced body weight gain; a...

OBJECTIVE This study investigated whether some components of the extracellular matrix and CD68 expression may drive the differences between the central giant cell granuloma (CGCG) of the jaws and giant cell tumor (GCT) of long bones, which present distinct evolution and clinical behavior. MATERIAL AND METHODS Eight cases of CGCG and 7 cases of GCT were selected and immunohistochemically analy...

Tumor necrosis factor-related, activation-induced cytokine (TRANCE), a tumor necrosis factor family member, mediates survival of dendritic cells in the immune system and is required for osteoclast differentiation and activation in the skeleton. We report the skeletal phenotype of TRANCE-deficient mice and its rescue by the TRANCE transgene specifically expressed in lymphocytes. TRANCE-deficient...

Case description- A three-month-old male German Shepherd dog, with signs of instability to stand, ataxia and radiographic symptoms of chondrodysplasia is presented. The symptoms were developed since birth.Clinical Findings- On physical examination, the affected pup did not show any swelling, pain or other abnormality in the long bones by palpation, but he had ataxia in walking. Ocular examinati...

OBJECTIVE To review the results of the management of infected non-union of long bones using the Illizarov fixator. METHODS Eight patients with non-union of long bones associated with current or prior infection were treated between 1998 and 2006. Seven patients were treated between 2004 and 2006. There were seven males and one female with an average age of 32 years (range 17-53 years). Four no...

Fracture healing is a complex process in which mechanical forces are essential for the regeneration of bone tissue. Mechanical loading can induce osteogenesis through the process of mechanotransduction. Current data on how mechanical loading stimulates fracture healing in weight-bearing long bones are presented. The role of mechanosensors, loading-induced interstitial fluid flow, streaming pote...

Craniometaphyseal dysplasia is a rare bone disorder of unknown etiology characterized by overgrowth of the skull base or craniofacial bones and abnormal remodeling of the metaphyses of the long bones. We present a sporadic case of craniometaphyseal dysplasia associated with facial paralysis observed in a 4-year-old female, which emphasizes the importance of the early detection of accompanying l...