Intrasplenic injection of the HT-29 LMM metastatic human colon cancer line reproducibly results in hepatic metastasis formation in congenitally athymic mice. HT-29-15, a murine monoclonal antibody (mAb) of the IgG1 class reactive with the HT-29 LMM line, and BL-3, an isotype-matched control antibody, were labeled with 125I. Labeled mAbs were injected i.v. in mice with hepatic metastases, and an...

Scaling effect of area-averaged NDVI is known as a source of error induced by differences in spatial resolution of two independent measurements over a fixed area. It deteriorates accuracy in parameter retrieval via NDVI, thus its mechanism needs to be fully understood for a better rectification of NDVI. The objective of this study is to investigate error bounds of averaged NDVI within a fixed a...

Hyperspectral unmixing decomposes the observed mixed spectra into a collection of constituent pure material signatures and associated fractional abundances. Because universal modeling ability neural networks, deep learning (DL) techniques are gaining prominence in solving hyperspectral analysis tasks. The autoencoder (AE) network has been extensively investigated linear blind source unmixing. H...

The approach called the Lexicographic Min-Max (LMM) optimization depends on searching for solutions minimal according to the lex-max order on a multidimensional outcome space. LMM is a refinement of the standard Min-Max optimization, but in the former, in addition to the largest outcome, we minimize also the second largest outcome (provided that the largest one remains as small as possible), mi...

We investigated the influence of prosodic structure and information density on vowel space size. Vowels were measured in five languages from the BonnTempo corpus, French, German, Finnish, Czech, and Polish, each with three female and three male speakers. Speakers read the text at normal, slow, and fast speech rate. The Euclidean distance between vowel space midpoint and formant values for each ...

Colombian Arabica coffee beans were roasted to give light, medium, and dark samples. Their aqueous extracts were analyzed by gel filtration chromatography, UV-visible spectrophotometry, capillary electrophoresis, and the ABTS(*)(+) assay. A progressive decrease in antioxidant activity (associated mainly with chlorogenic acids in the green beans) with degree of roasting was observed with the sim...

Applications of linear mixed models (LMMs) to problems in genomics include phenotype prediction, correction for confounding in genome-wide association studies, estimation of narrow sense heritability, and testing sets of variants (e.g., rare variants) for association. In each of these applications, the LMM uses a genetic similarity matrix, which encodes the pairwise similarity between every two...

The generalized linear mixed models (GLMMs) for clustered data are studied when covariates aremeasured with error. Themost conventional measurement error models are based on either linear mixed models (LMMs) or GLMMs. Even without the measurement error, the frequentist analysis of LMM, and particularly of GLMM, is computationally difficult. On the other hand, Bayesian analysis of LMM and GLMM i...

The scalability of statistical estimators is of increasing importance in modern applications. One approach to implementing scalable algorithms is to compress data into a low dimensional latent space using dimension reduction methods. In this paper we develop an approach for dimension reduction that exploits the assumption of low rank structure in high dimensional data to gain both computational...

Myosins from the following sources were purified by diethylaminoethyl-Sephadex chromatography: moytubes grown in vitro for 7-8 days, prepared from pectoralis muscles of 10-day old embryos, and breast and leg muscles from 16-day old embryos. The adenosine triphosphatase activities of these myosins were close to that of adult m. pectoralis myosin. The light chains of the embryonic myosins had the...