Background: Vaccination against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is recommended for patients with chronic liver diseases as the vaccine can prevent and/or reduce severity of SARS-CoV-2 infection. However, we have little information on often-reported liver-related adverse events (LrAEs) caused by mRNA vaccine. Methods: We retrospectively investigated frequency and det...

ABSTRACT Aim: Corona virus disease 2019 (COVID-19) mainly affects the lungs. However, other organs are affected as well. This article aimed to evaluate effects of coronavirus infection on liver density in addition laboratory findings. Methods: Biochemical parameters and non-contrast tomography images patients who presented pandemic clinic were studied retrospectively. Densities right left lobes...

Platelet endothelial cell adhesion molecule-1 (PECAM-1, CD31) is known to play an important role in hepatic inflammation. Therefore, we investigated the role of PECAM-1 in wild-type (WT) and knock-out (KO)-mice after single-dose liver irradiation (25 Gy). Both, at mRNA and protein level, a time-dependent decrease in hepatic PECAM-1, corresponding to an increase in intercellular cell adhesion mo...

background chronic hepatitis b virus (hbv) infection has a broad spectrum of manifestation, ranging from silent carrier state to advanced cirrhosis and hepatocellular carcinoma. the persistence of hbv dna in serum and hepatocytes of the cirrhotic patient could be detected by molecular techniques in spite of negative hbv serologic markers. conclusions the prevalence of obi was relatively high in...

BACKGROUND Little is known of the prevalence of hepatitis B virus (HBV) infection and its effect on choice of therapy and disease course in patients with inflammatory bowel disease (IBD). We assessed the prevalence of HBV in Hong Kong as well as determinants of altered transaminases, effects of HBV infection on therapeutic strategy and clinical course in IBD. METHODS In this retrospective coh...

Histoplasmosis is an endemic mycosis in the Ohio and Mississippi River valleys and can cause disseminated infection in immunocompromised hosts. Disseminated histoplasmosis is often respiratory in nature and most cases in transplant patients occur within 2 years post-transplantation. A 32-year-old male on mycophenolate and tacrolimus who underwent an orthotopic liver transplantation 10 years pri...

Aim : To study the curative effect of Sapindus mukorossi and Rheum emodi extracts in CCl4 induced liver cirrhosis in male rats. Methods : The dried powder of S. mukorossi & R. emodi was extracted successively with petroleum ether, benzene, chloroform and ethanol and concentrated in vacuum. The curative effect of the extracts of the fruit pericarp of S. mukorossi and rhizomes of R. emodi was stu...

An apparent epidemic cluster of toxic liver disease was reexamined among workers exposed to the solvent dimethylformamide. A demographically similar but unexposed group from a preemployment population was used for comparison. Analysis, after data transformation of the liver transaminases, revealed significant differences between the two populations with respect to the serum glutamic pyruvic tra...

BACKGROUND Cystinosis is a metabolic disease characterized by accumulation of cystine in different organs and tissues, leading to potentially life-threatening organ dysfunction. Infantile cystinosis typically leads to end-stage renal disease, necessitating renal replacement therapy. Liver disease in cystinosis is rare and is mostly reported as nodular regenerative hyperplasia leading to portal ...

Marasmus is a severe form of protein-calorie malnutrition characterized by the depletion of fat stores, muscle wasting, and the lack of edema. In developed countries, marasmus is often the result of anorexia nervosa. Abnormal transaminases with liver synthetic dysfunction have rarely been reported with anorexia nervosa. To our knowledge, we report the first detailed case of acute liver injury w...