نتایج جستجو برای: liver mitochondria
تعداد نتایج: 366152 فیلتر نتایج به سال:
The TiO2, which is a main material in the field of photocatalytic reactions, includes rutile and anatase phase. Titanium dioxide has possessed notice due to its promising applications in the environmental photocatalytic degradation of pollutants of organic compound in waste water and utilization of solar energy. The nanosized manganese titanate (pyrophanite) MnTiO3 was collected by oxidation of...
Hepatic ischemia-reperfusion injury is a phenomenon in which exacerbating damage of liver cells due to restoration blood flow following ischemia during surgery, especially those involving transplantation. Mitochondria, the energy-producing organelles, are crucial for cell survival and apoptosis have evolved range quality control mechanisms maintain homeostasis mitochondrial network response var...
The in vitro biological activity of secalonic acid D, a mycotoxin from Aspergillus ochraceus, was studied to assess its cytotoxicity for isolated rat liver mitochondria. Secalonic acid D uncoupled the oxidative phosphorylation of mitochondria and caused a mild inhibition of state 3 respiration. Secalonic acid D weakly enhanced latent ATPase activity in mitochondria but suppressed 2,4-dinitrophe...
The early effect of the administration of hydrocortisone on the liver parenchymal cell and thymus lymphocyte was followed chronologically with respect to (a) the contents of nucleic acid and protein and (b) the ultrastructural integrity of the subcellular components. In the electron microscopic study, morphometric and stereographic techniques combined with statistical analysis were applied for ...
This study examined the toxic effects of microcystins on mitochondria of liver and heart of rabbit in vivo. Rabbits were injected i.p. with extracted microcystins (mainly MC-RR and -LR) at two doses, 12.5 and 50 MC-LReq. microg/kg bw, and the changes in mitochondria of liver and heart were studied at 1, 3, 12, 24 and 48 h after injection. MCs induced damage of mitochondrial morphology and lipid...
1. [14C]Malonyl-CoA bound to intact mitochondria isolated from rat liver and heart in a manner consistent with the presence of two independent classes of binding sites in each tissue. 2. The binding characteristics for mitochondria obtained from fed male rats were: for heart, KD(1) = 1 -l8 nM, KD(2) = 30uM, N1 = 7pmol/mg of protein, N2 = approx. 660pmol/mg of protein; for liver, KD(1) = 0.1 M, ...
Assay of ornithine transcarbamylase and carbamyl phosphate synthetase I in submitochondrial fractions of rat liver mitochondria shows they are located primarily in the mitochondrial matrix. Therefore during the urea cycle ornithine must pass from the cytoplasm, where it is formed, to the mitochondrial matrix, where it is carbamylated. The resulting citrulline must then pass from the matrix to t...
Chicken liver synthesizes glucose from lactate and dihydroxyacetone at high rates but pyruvate, glycerol, alanine, and other amino acids are poor glucose precursors. Despite its limited conversion to glucose, 1 m~ pyruvate completely suppressed ketone body synthesis from octanoate by perfused chicken liver, whereas lactate at this concentration had no effect on ketogenesis. Also, increasing the...
Mitochondria were isolated from a slow-growing (9618A) and two intermediate-to-fast-growing (5123C, 5123tc) Mor ris hepatomas and host livers. The mitochondria! proteins were solubilized and fractionated on sodium dodecyl sulfate:polyacrylamide slab gels. One Coomassie bluestained band was absent or reduced in amount in all tumors relative to host livers. In addition, a major mito chondria! enz...
Mitochondria from regenerating liver of normal and alloxan-diabetic rats were assayed polarographically for respi ratory rate and oxidative phosphorylation. Approximately 65 to 70% of the liver was temoved by a simple surgical procedure, and the animals were sacrificed at different intervals from 16 hr to 4 weeks after partial hepatectomy. Mitochondria were isolated in a sucrose/tris(hydroxymet...
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