Hepatocellular carcinoma (HCC) occurs in patients with chronic liver damage, inflammation and cirrhosis. The facilitators involved increasing the HCC risk damaged are yet to be discovered. Diet lifestyle have a profound effect on HCC. term “gut axis” describes bidirectional relationship between gut, which both anatomically functionally related. Chronic damage is characterised by increased intes...

Liver dysfunction is common with COVID-19 infection, and the prevalence higher in men as well elderly. Manifestations of liver damage such high aspartate aminotransferase alanine activity, increased bilirubin levels, low albumin prolonged prothrombin time are associated severe infection. Mortality patients diffuse diseases without cirrhosis infection was 12 %, presence up to 40%, decompensated ...

The pathogenetic mechanisms for liver damage in acute hepatitis C are not clear, but a host immune cellular response may be involved. In chronic hepatitis C, there is strong evidence that host cellular immune response is involved in the control of viral replication and contributes to hepatocellular damage. As hepatitis C virus infection persists, continuous liver damage and regeneration, togeth...

The features of viral hepatitis B (HB) and C (HC) in the initial making these diagnoses three age groups men women (25-30, 31-55 years old for 31-60 men, over 55 60 men) were studied. High levels bilirubin blood serum all indicated damage functions hepatocytes, especially with B, C. high ALT activity an increase cytolytic processes liver hepatocytes HB HC, younger group, middle-aged groups. con...

Hemorrhagic shock is a frequent cause of liver failure and often leads to a fatal outcome. Several studies have revealed that p38 MAPK is a key mediator in hemorrhagic damage of the primary organs through the activation of proinflammatory cytokines such as tumor necrosis factor (TNF)-α and interleukin (IL)-1β. However, the precise role of these factors in liver damage following hemorrhagic shoc...

Objective(s):One cause of cigarette smoking is oxidative stress that may alter the cellular antioxidant defense system, induce apoptosis in lung tissue, inflammation and damage in liver, lung, and kidney. It has been shown that Chinese green tea (CGT) (Lung Chen Tea) has higher antioxidant property than black tea. In this paper, we will explore the preventive effect of CGT on cigarette smoke-in...

Sepsis induces hepatic injury but whether alpha-2 adrenoceptor (α2-AR) modulates the severity of sepsis-induced liver damage remains unclear. The present study used lipopolysaccharide (LPS) to induce hepatic injury and applied α2-AR agonist dexmedetomidine (DEX) and/or antagonist yohimbine to investigate the contribution of α2-AR in LPS-induced liver injury. Our results showed that LPS resulted...

Although tests of liver function have been studied for many years, it is only recently that any intensive comparative studies have been made (1 to 3). Liver function studies are performed (a) to detect hepatic damage, (b) to aid in prognosis and assist in determining any surgical risk, (c) to differentiate obstructive from nonobstructive jaundice. The detection of hepatic damage is complicated ...

conclusions co-occurrence of pbc with wd is rare, which can cause diffusely intrahepatic copper deposition. early liver biopsy and genetic testing are necessary for the diagnosis. the combination of ursodeoxycholic acid with zinc and sodium dimercaptopropane sulfonate is effective. introduction both primary biliary cirrhosis (pbc) and wilson’s disease (wd) can cause copper retention in the live...

Real-time monitoring of cellular and organ conditions improves our understanding of various physiopathological phenomena. Such monitoring is expected to provide important alternatives for clinical diagnosis and therapy. We have sought to show physiopathological changes of organs as well as cells. Here, we present an example of in vivo imaging of liver states using the luciferase-based caspase-3...