The possibility of usage polymer nanocomposites is being intensively studied today with a purpose their application in medicine, espessialy oncology. At the experimental stage it important to determine mechanisms influence such compounds on body and own possible undesirable effects. Aim – study effect treatment maximal doses dextran-polyacrylamide polymers as carriers silver gold nanoparticles ...

During inflammatory processes, immunocompetent cells are exposed to substantial amounts of free radicals and toxic compounds. Glutathione is a cysteine-containing tripeptide that an important ubiquitous antioxidant molecule produced in human organs. The intracellular content GSH regulates the detoxifying capacity cells, as well immune response. particularly liver, where it serves major non-prot...

Currently, liver transplantation has reached a level of maturity where it is considered an effective treatment for end-stage disease and can significantly prolong the survival time patients. However, acute chronic rejection remain major obstacles to its efficacy. Although long-term use immunosuppressants prevent rejection, associated with serious side effects significant economic burden Therefo...

Currently, liver transplantation is the most effective treatment for end-stage disease. Immuno-suppressive agents are required to be taken after operations, which have significantly reduced rejection rates and improved short-term (<1 year) survival rates. However, post-transplant complications related immuno-suppressive therapy led development of new protocols aimed at protecting renal funct...

Wilson disease (WD), known as hepatolenticular degeneration (HLD), is a treatable autosomal recessive disorder of copper metabolism. Because deposits in the liver first, not only original defective organ but also most affected organ. The injury one main causes death throughout course disease. Therefore, treatment task WD treatment, which great significance to improve prognosis patients. Autopha...

Histopathological effects of different sublethal concentrations (1, 2 and 4 mg/l) of diazinon, an organophosphorus pesticide, on gill, liver, spleen and kidney of grass carp (Ctenopharyngodon idella) were studied after 1, 7, 15, 30 and 45 days post-exposing fishes weighting 850 ± 155 g to the toxicant for 12 hours at 18-22ºC. In addition, tissues of nostril were examined for transmission electr...

Histopathological effects of different sublethal concentrations (1, 2 and 4 mg/l) of diazinon, an organophosphorus pesticide, on gill, liver, spleen and kidney of grass carp (Ctenopharyngodon idella) were studied after 1, 7, 15, 30 and 45 days post-exposing fishes weighting 850 ± 155 g to the toxicant for 12 hours at 18-22ºC. In addition, tissues of nostril were examined for transmi...