Hepatic solitary fibrous tumor (SFT) is a rare tumor originating from the mesenchyme. Here we report a new case of SFT in the liver and review the clinical presentation, radiological and operative findings, diagnosis, treatment, and outcome. The patient was a 59-year-old man who presented with progressive fatigue for 3 months and an abdominal mass for 3 days. On laboratory tests, no abnormality...

BACKGROUND Cisplatin (CP) is widely used in clinic to treat the solid tumors. However, CP is associated with some major side effects including nephrotoxicity, hepatoxicity, and testicular toxicity. OBJECTIVES To found, which of the toxicities is the first side effect of CP. MATERIALS AND METHODS we conducted a pilot research on 12 adult male Wistar rats. RESULTS One week after CP administ...

Circulation. 2017;135:808–811. DOI: 10.1161/CIRCULATIONAHA.116.026903 808 ECG CHALLENGE A 59-year-old man presented to our hospital reporting 3 months of exertional dyspnea, ortopnea, paroxysmal nocturnal dyspnea, and lower leg edema. On physical examination, he had jugular venous distention, bibasilar rales, large tender liver, and peripheral edema. On cardiac auscultation, he had a regular he...

Five patients showing a normal to near-normal BSP test and a marked delay in ICG plasma clearance, and two families with clustering of the same abnormality, are described. Two had Gilbert's syndrome, one was convalescing from acute hepatitis, and the other two had no detectable liver abnormality. Measured indices of ICG metabolism indicated a marked reduction in the hepatic uptake, storage capa...

background kaposi sarcoma (ks) is an angioproliferative tumor that mainly involves mucocutaneous tissues, but extracutaneous spread to lymph nodes, gi tract, lungs, liver, pancreas, heart, and testes can occur in aids-associated ks. patients with pulmonary ks may be symptomatic or present with an asymptomatic abnormality on chest radiography. patient and method a 28-year-old man presented with ...

Pulmonary abnormalities and symptoms are common in patients with chronic liver disease. If questioned, up to 70% of cirrhotic patients undergoing evaluation for liver transplantation complain of dyspnea.1 In screening studies of patients with chronic liver disease, arterial blood gas abnormalities are found in as many as 45% and abnormal pulmonary function tests in as many as 50%.2 A variety of...

A delay in liver regeneration after partial hepatectomy (PHx) leads to acute liver injury, and such delays are frequently observed in aged patients. BubR1 (budding uninhibited by benzimidazole-related 1) controls chromosome mitotic segregation through the spindle assembly checkpoint, and BubR1 down-regulation promotes aging-associated phenotypes. In this study we investigated the effects of Bub...

Although liver function test abnormality is frequently noted in children, there is no report about the distribution of the etiology and natural recovery time of the abnormal liver function. From March 2005 to February 2014, clinical information was retrospectively collected from 559 children who had abnormal liver function and were hospitalized or visited the outpatient clinic at the Jeju Natio...

OBJECTIVE The biological importance of calcifications occasionally noted in fetal tissues (mainly liver) at autopsy or ultrasound is largely unexplored. Previous reports hint at an association to infection, circulatory compromise, malformations or chromosomal abnormalities. To identify factors associated with calcifications, we have performed a case-control study on the largest cohort of fetuse...