mammea africana sabine (guttiferae) stembark, a common plant, traditionally used to treat various diseases and ailments was evaluated for hepatoprotective potentials against paracetamol- induced liver injury in rats. the hepatoprotective effect of the stembark extract (30-90 mg/kg) was evaluated by the assay of liver function parameters: total and direct bilirubin, serum protein and albumin, to...

objective: lamotrigine is an antiepileptic drug, widely used in the treatment of epilepsy; long-term use of this drug can cause hepatotoxicity. zingiber officinale roscoe (ginger) possesses antioxidant properties. in present research, the effect ofhydroalcoholic extract of ginger (heg) on the liver of lamotrigine-treated epileptic rats was investigated material and methods: forty-eight female w...

background: liver transplantation (lt) is now performed as a cure of numerous untreatable pediatric liver diseases. quality of life (qol) can be affected in pediatric patients with lt. many factors are responsible for lower scores of qol. this article aims to detail qol in liver recipients 6 months after lt in children. methods: qol assessed using child health quality-parent form 50 for parents...

a young man presented with a large liver mass and positive hepatitis b virus markers. this 18-year-old male has developed ascites, jaundice, high serum alpha fetoprotein (afp) level, liver mass and portal hypertension, without fever or calcification in the mass. all favored the diagnosis of rapidly, progressive hepatocellular carcinoma, however proven hepatoblastoma in liver biopsy. hepatoblast...

background nonalcoholic steatohepatitis (nash) is a common liver disease that can progress to cirrhosis or hepatocellular carcinoma. it is estimated that up to 3% of the iranian population have this condition. although the pathogenesis of nash is incompletely understood, there is significant evidence pointing to the importance of insulin resistance. metformin is an oral hypoglycemic agent known...

0

conclusions in our population of cirrhotic patients, treatment of variceal bleeding predisposed the patients to portal vein thrombosis, but hypercoagulable disorders by themselves were not associated with portal vein thrombosis. results there was no statistically significant difference in the assessed hypercoagulable states between patients with or without portal vein thrombosis. a history of p...

context the pnpla3 i148m variant has been recognized as a genetic determinant of liver fat content and a genetic risk factor of liver damage progression associated with steatohepatitis. the i148m variant is associated with many chronic liver diseases. however, its potential association with inflammatory and autoimmune liver diseases has not been established. evidence acquisition we systemically...

background: the frequency of sonographic report of liver fat infiltration in asymptomatic person is increasing. the aim of this study was evaluation of liver function and detection of frequency of metabolic syndrome and insulin resistance in asymptomatic persons with fatty liver in sonographic examinations. materials and methods: seventy six patients with fatty liver in sonographic examination ...