lipotoxicity

نتایج جستجو برای: lipotoxicity

تعداد نتایج: 1097 فیلتر نتایج به سال:

Lipotoxicity and Diabetic Nephropathy: Novel Mechanistic Insights and Therapeutic Opportunities

Journal: :International Journal of Molecular Sciences 2020

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Skeletal muscle lipotoxicity in insulin resistance and type 2 diabetes

Journal: :The Journal of Physiology 2009

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Fetuin-A aggravates lipotoxicity in podocytes via interleukin-1 signaling

Journal: :Physiological Reports 2017

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Cardiac steatosis is associated with excess body weight in otherwise healthy adults

2011

Rajarshi Banerjee Belen Rial Joseph J Suttie Pete Cox Adam J Lewandowski Andrew Johnson Oliver Rider Cameron Holloway Jane Francis Matthew D Robson Jurgen Schneider Kieran Clarke Paul Leeson Stefan Neubauer

Background and aim Obesity confers an enormous burden of cardiovascular morbidity and mortality worldwide. Lipotoxicity has been implicated as a potential common pathway in myocyte dysfunction and ultimately apoptosis. Fat deposition in the peritoneum, the liver and around vascular structures has been linked to metabolic syndrome and subsequent cardiomyopathy. Therefore this study sought to det...

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Type 1 diabetic cardiomyopathy in the Akita (Ins2) mouse model is characterized by lipotoxicity and diastolic dysfunction with preserved systolic function

2009

Ratnadeep Basu Gavin Y. Oudit Xiuhua Wang Liyan Zhang John R. Ussher Gary D. Lopaschuk Zamaneh Kassiri

Basu R, Oudit GY, Wang X, Zhang L, Ussher JR, Lopaschuk GD, Kassiri Z. Type 1 diabetic cardiomyopathy in the Akita (Ins2) mouse model is characterized by lipotoxicity and diastolic dysfunction with preserved systolic function. Am J Physiol Heart Circ Physiol 297: H2096 –H2108, 2009. First published October 2, 2009; doi:10.1152/ajpheart.00452.2009.—Diabetic cardiomyopathy is an important contrib...

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