نتایج جستجو برای: lipid correcting agent
تعداد نتایج: 428229 فیلتر نتایج به سال:
Administration of chloramphenicol early in Ccl, intoxication prevents lipid peroxidation of endoplasmic reticulum membranes. Conversely, a sulfamoyl analog, Tevenel, was ineffective in preventing the lipoperoxidative process. Likewise, in an in vitro microsomal system chloramphenicol inhibited a lipid peroxidation process and Tevenel did not. However, both compounds bind to cytochrome P-450. Ch...
D-galactosamine is a hepatotoxic agent, which induces diffuse injury of liver tissue followed by the regeneration process. Our data showed a high increase of serum aminotransferases after D-galactosamine administration, which indicates a high extent of liver injury. When lipid emulsion was applied immediately after D-galactosamine, the increase of serum aminotransferases was greatly reduced. In...
Atorvastatin calcium, the lipid lowering agent, is taken as a model drug characterized by poor water solubility and bioavailability. In this study an attempt was made for preparation of nanocrystals using high pressure homogenization. A number of stabilizers were included as well as polymers at different concentrations, and the formulations were homogenized for ten cycles at a pressure of 1000 ...
The synthesis of RNA molecules carrying lipids at their 3'-termini and 5'-termini is reported. These conjugates were fully characterized by MALDI-TOF mass spectrometry and HPLC chromatography. The ability of these conjugates to silence gene expression was evaluated in the inhibition of the tumor necrosis factor. All the lipid-siRNA derivatives were compatible with RNA interference machinery if ...
Purpose Methods Via CMR (1.5T GE), 707-two mm contiguous in vivo slices of advanced carotid disease (>50%; mean 64±21 ) representing 42 complete bilateral human plaques (age 68±15yrs) were analyzed for 2D/3D extent of vascular wall: lipid pool, fibrous cap, outer wall area (OWA), vessel wall area (VWA), lumen area (LA) and lipid pool (LP). All were related to fasting lipids relative to %stenosi...
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