The objective of the research is to optimize the empennage of a light weight aircraft such as Zenith aircraft. The case is specified by a unique set of geometry, materials, and strength-to-weight factors. The anticipated loads associated with the empennage structure are based on previous light aircraft design loads. These loads are applied on the model to analyze the structural behavior conside...

Squamous cell carcinoma (SCC) is an epithelial malignancy involving many anatomical sites and is the most common cancer capable of metastatic spread. Development of early diagnosis methods and novel therapeutics are important for prevention and mortality reduction. In this effort, numerous molecular alterations have been described in SCCs. SCCs share many phenotypic and molecular characteristic...

Skin is the largest organ in human body. UV light exposure responsible for development of Non-melanoma skin cancer, most common type cancer worldwide, classified Basal Cell Carcinoma (BCC) and Squamous (SCC). SCC less but more aggressive invasive than BCC. Lately, Actinic keratosis (AK; its precursor lesion) treatment has been evolving from just resection to non-invasive therapies such as Photo...

Caveolin-1 (Cav-1), a major structural protein of caveolae, is an integral membrane protein which plays an important role in the progression of carcinoma. However, whether Cav-1 acts as a tumor promoter or a tumor suppressor still remains controversial. For example, the tumor-promoting function of Cav-1 has been found in renal cancer, prostate cancer, tongue squamous cell carcinoma (SCC), lung ...

CD44, a cell surface proteoglycan, is involved in multiple biological events. CD44 transcripts undergo tissue-dependent alternative splicing, resulting dozens of functionally distinct isoforms. However, the nature these isoforms human skin has not been adequately determined. Recently, we isolated and designated all 18 unique by cloning strategy. In our previous study, found that expression tran...

  Introduction: Esophageal Squamous-Cell Carcinoma (SCC) is one of the most common malignancies in Iran. To reduce the incidence of esophageal SCC, it is important to recognize the controllable risk factors and prevent them. Celiac disease is widely known as a possible risk factor for esophageal SCC.  Thus, we decided to assess the frequency of celiac disease in esophageal SCC patients in North...

The incidence rates of skin cancer in Australia are the highest in the world. In 2002 the age-standardised incident rate for basal cell carcinoma (BCC) was estimated to be 884 per 100,000 of the population. This rate showed a threefold gradient between northern and southern Australia [1]. BCCs are the most common cutaneous tumours, accounting for approximately 70% of all malignant diseases of t...

Background CoNS species are likely reservoirs of the staphylococcal cassette chromosome mec (SCC mec ) in Staphylococcus aureus . S . aureus CC395 is unique as it is capable of exchanging DNA with CoNS via bacteriophages, which are also known to mediate transfer of SCC mec . Objectives To analyse the structure and putative origin of the SCC mec element in S . aureus CC395. Methods The only ...

AIMS Squamous cell carcinoma of the skin (SCC) increases dramatically in organ transplant recipients (OTRs). The aim was to determine whether qualitative and quantitative differences in perineoplastic inflammation in OTRs contribute to the increased carcinogenesis. METHODS AND RESULTS We studied the perineoplastic inflammatory infiltrate in SCC, assessing depth, density and phenotype (CD3, 4,...

introduction: 90% of the tumors in the head and neck are squamous-cell carcinomas (hnscc), which have overall 5- year survival rate between 50% -60%. cd44 has been shown to be associated with the prognosis.  materials and methods: biopsy specimens of 51 patients with oral tongue scc were evaluated by immunohistochemistry (ihc) for the cd44 antibody.  results: there was no significant correlatio...