Nanoporous gold (np-Au) is a promising multifunctional material for neural electrodes. We have previously shown that np-Au nanotopography reduces astrocyte surface coverage (linked to undesirable gliosis) while maintaining high neuronal coverage in a cortical primary neuron-glia co-culture model as long as two weeks in vitro. Here, we investigate the potential influence of secreted soluble fact...

The purpose of implementation-based testing is to gain a measure of confidence in the correctness of the software by providing adequate coverage of the code. One unit of testing in object-oriented software is a class. However, classes use other classes and if class interactions form a cycle of dependencies then, to test a client class that uses an untested supplier class, stubs must be construc...

Background and aim: Postpartum haemorrhage remains one of the main leading causes of maternal mortality across the world. This is despite a wide-spread coverage of active third stage of labour care in many countries.  Reflecting on emerging evidence in this context, a discussion of associated factors which should be considered in interpretation of the evidence and its implications is presented ...

Background Across Western Europe, procedures and formalised criteria for taking decisions on the coverage (inclusion in the benefits basket or equivalent) of healthcare technologies vary substantially. In the decision documents, which display the justification of, the rationale for, these decisions, national healthcare institutes ma...

Background and Objectives: Patient readmission is an important criterion in performance evaluation of healthcare settings. Identifying the causes of the readmissions would help the policymakers in designing strategies for efficient management of health facilities. This stud aimed to explore factors contributing to readmission by sampling from an Iranian hospital. Methods: Clinical records of ...

BACKGROUND Studies on plant communities in the Amazon have reported that different hydro-edaphic conditions can affect the richness and the species composition of different ecosystems. However, this aspect is poorly known in the different savanna habitats. Understanding how populations and plant communities are distributed in these open vegetation areas is important to improve the knowledge abo...

Increasing Coverage of Antiretroviral Therapy and Male Medical Circumcision in HIV Hyperendemic Countries: A Cost-Benefit Analysis HIV continues to cause the largest number of disability-adjusted life years of any disease in HIV hyperendemic countries (i.e., countries with an adult HIV prevalence >15%). We compare the benefits and costs of two proven biological interventions to reduce the healt...

Vietnam has pursued universal health insurance coverage for two decades but has yet to fully achieve this goal. This paper investigates the barriers to achieve universal coverage and examines the validity of facilitating factors to shorten the transitional period in Vietnam. A comparative study of facilitating factors toward universal coverage of Vietnam and Korea reveals significant internal f...

A prospective study was carried out over the 10 years 1978-87 to determine the incidence and implications of sudden death in road users--that is, drivers, pedestrians, cyclists, and motorcyclists. During the study period 30,000 patients were seen in the same accident and emergency departments of East Berkshire after road traffic incidents or accidents, of whom 267 either were brought in dead or...

In this article, we study the assessment of the reliability of redundant systems with imperfect fault coverage. We term fault coverage the ability of a system to isolate and correctly accommodate failures of redundant elements. For highly reliable systems, such as avionic and space systems, fault coverage is in general imperfect and has a significant impact on system reliability. We review here...