نتایج جستجو برای: licorice extract

تعداد نتایج: 177627  

2015
Nu Ry Song Jong-Eun Kim Jun Seong Park Jong Rhan Kim Heerim Kang Eunjung Lee Young-Gyu Kang Joe Eun Son Sang Gwon Seo Yong Seok Heo Ki Won Lee

Licorice is a traditional botanical medicine, and has historically been commonly prescribed in Asia to treat various diseases. Glycyrrhizin (Gc), a triterpene compound, is the most abundant phytochemical constituent of licorice. However, high intake or long-term consumption of Gc has been associated with a number of side effects, including hypertension. However, the presence of alternative bioa...

Journal: :Journal of chromatography. B, Biomedical sciences and applications 1999
C P Guillaume J C van der Molen M N Kerstens R P Dullaart B G Wolthers

A sensitive and quantitative gas chromatographic assay for the determination of 18 beta-glycyrrhetinic acid (18 beta-GA), the main metabolite of glycyrrhizin after oral licorice consumption in human urine, has been developed and validated. For the extraction of 18 beta-GA from urine two Sep-Pak C18 extractions, hydrolysis with Helix pomatia and three liquid-liquid extractions were performed, us...

Journal: :Cancer prevention research 2013
Nu Ry Song Eunjung Lee Sanguine Byun Jong-Eun Kim Madhusoodanan Mottamal Jung Han Yoon Park Soon Sung Lim Ann M Bode Hyong Joo Lee Ki Won Lee Zigang Dong

Licorice root is known to possess various bioactivities, including anti-inflammatory and anticancer effects. Glycyrrhizin, a triterpene compound, is the most abundant constituent of dried licorice root. However, high intake or long-term consumption of glycyrrhizin causes several side effects, such as hypertension, hypertensive encephalopathy, and hypokalemia. Therefore, finding additional activ...

2012
Yuka Watanabe Nobutomo Ikarashi Toshiyuki Satoh Kiyomi Ito Wataru Ochiai Kiyoshi Sugiyama

We have studied the effects of various Kampo medicines on P-glycoprotein (P-gp), a drug transporter, in vitro. The present study focused on Daiokanzoto (Da-Huang-Gan-Cao-Tang), which shows the most potent inhibitory effects on P-gp among the 50 Kampo medicines studied, and investigated the P-gp inhibitory effects of Daiokanzoto herbal ingredients (rhubarb and licorice root) and their components...

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