Long-segment urethral stricture or panurethral stricture disease, involving the different anatomic segments of anterior urethra, is a relatively less common lesion of the anterior urethra compared to bulbar stricture. However, it is a particularly difficult surgical challenge for the reconstructive urologist. The etiology varies according to age and geographic location, lichen sclerosus being t...

OBJECTIVE To generate a list of items through international expert consensus consisting of both symptoms and clinical signs for inclusion in an adult vulvar lichen sclerosus severity scale. METHODS This study was carried out as a three-stage Delphi consensus exercise. After an extensive literature review, any items used to determine disease severity in previous clinical trials were compiled i...

OBJECTIVES To describe the techniques and results of surgical reconstruction of glans penis lesions. METHODS Seventeen patients (mean age: 53.2 yr) were treated by resurfacing or reconstruction of the glans penis for benign, premalignant and malignant penile lesions. The aetiology of the lesions was one Zoon's balanitis, four lichen sclerosus, one carcinoma in situ, five squamous cell carcino...

OBJECTIVES To describe the clinicopathologic features of melanocytic proliferations associated with lichen sclerosus (LS) and to compare these findings with those in controls. DESIGN Cohort study. SETTING Academic and private practice dermatology and dermatopathology services. PATIENTS Cases of melanocytic proliferations associated with LS and consecutive controls with persistent (recurre...

1Department of Biology and Chemical Engineering, Jiangsu University of Science and Technology, Zhenjiang 212003, China 2College of Chinese Medicine Materials, Jilin Agricultural University, Changchun 130118, China 3Eco-friendly New Materials Research Group, Korea Research Institute of Chemical Technology, Daejeon 305-343, Korea 4Korean Lichen Research Institute, Sunchon National University, Sun...

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Lichen sclerosus (LS) is a chronic, inflammatory, mucocutaneous disorder of genital and extragenital skin. LS is a debilitating disease, causing itch, pain, dysuria and restriction of micturition, dyspareunia, and significant sexual dysfunction in women and men. Many findings obtained in recent years point more and more towards an autoimmune-induced disease in genetically predisposed patients a...

1. Sardella A. An up-to-date view on burning mouth syndrome. Minerva Stomatol. 2007;56:327-40. 2. Zakrzewska JM, Forssell H, Glenny M. Interventions for the treatment of burning mouth syndrome. Cochrane Database Syst Rev. 2005;25:CD002779. 3. Mínguez Serra MP, Salort Llorca C, Silvestre Donat FJ. Pharmacological treatment of burning mouth syndrome: A review and update. Med Oral Patol Oral Cir B...

Finally, familial cutaneous collagenoma must be differentiated from two distinct types of eruptive collagenoma. Eruptive collagenoma type 1 is clinically and histologically similar to familial cutaneous collagenoma but without documented familial inheritance. Eruptive collagenoma type 2 presents cutaneous lesions smaller than those of familial cutaneous collagenoma and arranged on the extremiti...