Lewy bodies and Lewy neurites are the hallmark neuropathologic findings in Parkinson disease, Parkinson disease with dementia, dementia with Lewy bodies, and other alpha-synucleinopathies. They have also been described in the brains of normal older individuals and referred to as incidental Lewy body disease. The purpose of this study was to determine the prevalence of Lewy bodies and Lewy neuri...

A neural network technique is used to quantify relationships involved in cloud–radiation feedbacks based on observations from the Surface Heat Budget of the Arctic (SHEBA) project. Sensitivities of longwave cloud forcing (CFL) to cloud parameters indicate that a bimodal distribution pattern dominates the histogram of each sensitivity. Although the mean states of the relationships agree well wit...

OBJECTIVES Dementia in Alzheimer's disease correlates closely with loss of neocortical synapses. Similar synaptic loss has been shown in patients whose Alzheimer's disease is also associated with neocortical and brain stem Lewy bodies. The aim was to determine if dementia in Lewy body disease was associated with diminished concentrations of midfrontal cortex synaptophysin. METHODS An immunobi...

α‐synuclein (Lewy Body) pathology is commonly found in the enteric nervous system (ENS) of patients diagnosed with Neurocognitive Disorder with Lewy Bodies (NCDLB) and Parkinson’s Disease (PD). Lewy pathology in the ENS can produce symptoms of bowel immotility, including constipation, obstipation, and bowel impaction. These symptoms significantly reduce the quality of life for the patient, prod...

Objective-Motor and cognitive function were compared in patients with Lewy body dementia, Parkinson's disease, or Alzheimer's disease, to identify features that may be clinically useful in differentiating Lewy body dementia from Alzheimer's disease and Parkinson's disease. Methods-A range of neuropsychological function and extrapyrimidal signs (EPS) was assessed in 16 patients with Lewy body de...

In 1913, the Breslau neurologist Lewy described globular inclusions of cytoplasmic condensations in the cells of the nucleus substantiae innominatae and the dorsal vagal nucleus in paralysis agitans. These cell inclusions have since been described by many other investigators. In 1923, Lewy also found them in the pigmented ganglion cells of the substantia nigra in Parkinson's disease. Tretiakoff...

In this paper, we develop a BTA algorithm that ensures termination of oo-line partial evaluation for rst-order functional programs, extending the work of Holst and of Glenstrup and Jones. Holst's characterization of in-situ-decreasing behaviour does not account for parameters that do not control the recursion of their functions. We extend Holst's framework to handle this phenomenon by deening t...