Human leptospirosis, or commonly known as the “rat urine disease” is a zoonotic disease caused by bacterium called Leptospira sp. acquired via of animal carriers. It believed that incidence rate leptospirosis has been under-reported due to its unspecific clinical Symptoms and limitations current diagnostic methods. Leptospirosis can be effectively treated with antibiotics in early stage, it cur...

Przy tu lsk i T., D. Porae czkowska: Genetic Markers of Resistance to Leptospirosis in Pigs of the Large White Polish Breed. Acta vet. Brno, 49, 1980: 237 -244. , Data obtained from 1200 Large White pigs in two farms show that in pigs producing Am BB, Akp AB, Pra AB or BB, Tf AB there is a significantly lower incidence of leptospirosis than in pigs producing Am AB, Akp BB or Be, Pra AA and Tf B...

Background. Leptospirosis is a spirochetal zoonosis with complex clinical features including renal and liver failure. Case report. We report the case of a Swiss fisherman presenting with leptospirosis. After initial improvement, refractory septic shock and severe liver and kidney failure developed. The expected mortality was estimated at 90% with clinical scores. The patient underwent plasma ex...

Leptospira interrogans serovar autumnalis, a causative agent of leptospirosis in Thailand, was isolated from a patient for DNA extraction and amplification of LipL32 gene by polymerase chain reaction (PCR). The 782 bp PCR product was obtained, which was inserted into pAE plasmid with polyhistidine (His6 tag) to construct pAE-LipL32. This recombinant plasmid was transfected into E. coli BL21 (DE...

Leptospirosis is an important zoonosis of worldwide distribution. It is uncommon for leptospirosis to present as a primary neurological disease. In this study of patients who presented with an acute neurological disease, and who were subsequently found to have leptospirosis, aseptic meningitis was the commonest manifestation. The other presentations were myeloradiculopathy, myelopathy, Guillain...

The incidence of leptospirosis in British troops serving in Malaya has afforded a good opportunity for the comparative evaluation of the clinical and laboratory examinations of a large number of mild cases of the disease, and the use of these tests in diagnosis and in the differentiation of leptospirosis from other causes of fever (Robinson and Kennedy, 1956; McCrumb, Stockland, Robinson, Turne...

We read the article by Dutta et al on “Leptospirosis An Overview” with interest.1 The problem in utilizing microscopic agglutination test (MAT) has been highlighted and we shall discuss briefly the current status of MAT. MAT is considered the gold standard test for diagnosis of leptospirosis. It has unsurpassed specificity, but its sensitivity is low compared to ELISA/SAT (Slide agglutination t...

UNLABELLED Leptospirosis is a commonly encountered type of zoonosis, especially in tropical regions. There is insufficient data regarding its frequency in non-tropical regions such as Turkey. Although leptospirosis presents with a mild icteric form in nearly 90% of cases, it can lead to Weils disease characterized by fever as well as fulminant hepatorenal and respiratory failure, in approximate...

Two cases of leptospirosis presenting with cough and haemoptysis are described, together with their pulmonary radiological features. The various radiological chest findings are reviewed together with the pathogenesis and pathology of the lesions. Although the pulmonary involvement due to a haemorrhagic pneumonitis in leptospirosis is usually an incidental finding, occasional:y it is the most pr...

We reviewed a series of 5 cases of leptospirosis treated in our hospital between 1998 and 2004 and found that lung involvement was observed in 3 of the 5 cases. All patients met the criteria for the diagnosis of leptospirosis. Weil syndrome was diagnosed in 4 patients and anicteric leptospirosis in 1 patient. The 3 patients with lung sequelae were admitted into the intensive care unit because o...