An exacerbated inflammatory response questions biomaterial biocompatibility, but on the other hand, inflammation has a central role in the regulation of tissue regeneration. Therefore, it may be argued that an 'ideal' inflammatory response is crucial to achieve efficient tissue repair/regeneration. Natural killer (NK) cells, being one of the first populations arriving at an injury site, can hav...

mTORC2 is aberrantly activated in cancer and therefore is considered to be an important therapeutic target. The hedgehog pathway, which is also often hyperactivated, regulates transcription of several genes associated with angiogenesis, metastasis, cellular proliferation and cancer stem cell (CSC) regeneration. However, the contribution of mTORC2 toward hedgehog pathway activity has not been ex...

Paired immunoglobulin-like receptor B (PIR-B) partially mediates the regeneration-inhibiting effects of the myelin-derived protein Nogo, myelin-associated glycoprotein (MAG), and oligodendrocyte-myelin glycoprotein (OMgp). In this study, we report that inhibition of the PIR-B signaling cascades in neurons enhances axon regeneration in the central nervous system (CNS). Binding of MAG to PIR-B le...

Plants are under constant attack from insects, microbes, and other physical assaults that damage or remove body parts. Regeneration is one common strategy among plants to repair their body plan. How do organisms that are proficient at regeneration adapt their developmental programs for repatterning tissues? A new body of research employing high-resolution imaging together with cell-fate markers...

This paper addresses socio-ecological, community-led resilience as the ability of urban system to progress and adapt. is based on socio-cultural, self-organized case study CanFugarolas in Mataró (Barcelona), for recovery a derelict industrial building given lack attention emerging from grassroots. Facing rigidities (stagnation) observed under provisions regeneration policies (regulatory realm),...

In order to enhance the display result of the LED display image, an improved algorithm of LED display image based on composed correction is proposed. Firstly, the correction principle and the development status of the current correction technologies of the LED display image is introduced, and the two main correction technologies are analyzed. Secondly, the theory of composed correction is propo...

Article history: Received 17 December 2014 Received in revised form 1 December 2015 Accepted 3 December 2015 Available online 19 December 2015 The data for the lightflux degradation and chromaticity shift of LED lamps exhibits a considerable amount of scatter due to intrinsic and extrinsic factors. In this study, some degradation models, such as the gamma process model, were reviewed in terms o...

Brachial plexus lesion results in loss of motor and sensory function, being more harmful in the neonate. Therefore, this study evaluated neuroprotection and regeneration after neonatal peripheral nerve coaptation with fibrin sealant. Thus, P2 neonatal Lewis rats were divided into three groups: AX: sciatic nerve axotomy (SNA) without treatment; AX+FS: SNA followed by end-to-end coaptation with f...