Robins (1993, 1994, 1997, 1998ab) has developed a set of causal or counterfactual models, the structural nested models (SNMs). This paper describes an alternative new class of causal modelsthe (non-nested) marginal structural models (MSMs). We will then describe a class of semiparametric estimators for the parameters of these new models under a sequential randomization (i.e., ignorability) assu...

25 26 This article describes the development, validation and application of a rapid screening method 27 for the detection and identification of undesirable organic compounds in aquaculture products. 28 A generic sample treatment was applied without any purification or preconcentration step. After 29 extracting the samples with acetonitrile/water 80:20 (0.1% formic acid), the extracts were 30 ce...

A new analytical method has been developed and is proposed for the rapid determination of eighteen common amino acids, including tryptophan, in plasma and dried blood spots, by liquid chromatography coupled with ionspray tandem mass spectrometry. Potentially the method can include other amino acids and can be used for the diagnosis of metabolic disease. The use of the ionspray tandem mass spect...

Purpose This paper aims to investigate the pass-through (PT) effect in Turkey by using quarterly data for period 1998: Q1-2019: Q2 understand dynamic potential effects of exchange rates on domestic prices. Design/methodology/approach The launches several nonlinear models which basic determinants prices are determined through Markov regime-switching (MSMs). Hence, this research follows variables...

Gluten proteins from wheat, rye, barley and, in rare cases, oats, are responsible for triggering hypersensitivity reactions such as celiac disease, non-celiac gluten sensitivity and wheat allergy. Well-defined reference materials (RM) are essential for clinical studies, diagnostics, elucidation of disease mechanisms and food analyses to ensure the safety of gluten-free foods. Various RM are cur...

Part of understanding a molecule's conformational dynamics is mapping out the dominant metastable, or long lived, states that it occupies. Once identified, the rates for transitioning between these states may then be determined in order to create a complete model of the system's conformational dynamics. Here we describe the use of the MSMBuilder package (now available at http://simtk.org/home/m...

Superoksida dismutase (SOD) merupakan enzim yang berfungsi sebagai antioksidan dalam tubuh. Antioksidan dapat menangkal radikal bebas ada Krokot bahan alternatif telah terbukti memiliki sifat antioksidan, namun belum diketahui apakah batang krokot meningkatkan aktivitas SOD dan jenis senyawa berperan tersebut. Penelitian ini bertujuan mengetahui potensi terhadap pada tersebut melalui penambatan...